Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients

NCT02351206 | Completed

• 1 other identifier: JS-CT-2014-05
• Study Type: observational
• Target: 389
• Locations: 0 countries
• Sites: N/A

Brief Summary

As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP. The investigators therefore assessed the feasibility of using X-ray disc space height measurements as a predictive evaluation method of lumbar disc herniation (LDH) and degeneration in LBP patients in their early 20s.

Conditions

Intervertebral Disc Displacement; Intervertebral Disc Degeneration; Low Back Pain

Keywords

X-Rays; Magnetic Resonance Imaging; Sensitivity and Specificity

Outcome Measures

Primary Outcomes (1)

• The distance between the 2 midpoints of the inferior and superior borders of the vertebral bodies surrounding the L4/5 intervertebral disc space divided by the AP diameter of the inferior border of the L4 vertebral body

  Baseline

Study Arms (2)

The experimental group

Patients with intervertebral disc protrusion, extrusion, or migration at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.

Radiation: x-ray, MRI

The control group

Patients with normal or disc bulging readings at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.

Radiation: x-ray, MRI

Interventions

x-ray, MRI RADIATION

The control group; The experimental group

Eligibility Criteria

• Age: 20 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Patients visiting Jaseng hospital of Korean Medicine, a spine specializing Korean medicine hospital designated by the Korean ministry of health and welfare, from January, 2010 to October 2014

You may qualify if:

• Age 20-25 years
• L-spine X-ray and L-spine MRIs taken within a week of the other test
• Native Korean ethnicity

You may not qualify if:

• Scoliosis with a Cobb's angle of ≥20°
• Significant vertebral deformity of any etiology (e.g. spondylolisthesis, fracture, spondylitis, neoplasm)
• Previous spinal surgery

Sponsors & Collaborators

• Jaseng Hospital of Korean Medicine: lead

MeSH Terms

Conditions

Intervertebral Disc Displacement; Intervertebral Disc Degeneration; Low Back Pain; Hypersensitivity

Interventions

X-Rays; Magnetic Resonance Spectroscopy

Condition Hierarchy (Ancestors)

Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Hernia; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Immune System Diseases

Intervention Hierarchy (Ancestors)

Electromagnetic Radiation; Electromagnetic Phenomena; Magnetic Phenomena; Physical Phenomena; Radiation; Radiation, Ionizing; Spectrum Analysis; Chemistry Techniques, Analytical; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 27, 2015
• First Posted: January 30, 2015
• Study Start: January 1, 2010
• Primary Completion: October 1, 2014
• Study Completion: November 1, 2014
• Last Updated: November 7, 2018

Record last verified: 2018-11