NCT02346981

Brief Summary

The purpose of the present study was to analyze the effect of 12 weeks of resistance training on post-exercise blood pressure (BP) and to to correlate the acute and chronic decrease in blood pressure (BP) following resistance training in normotensive older women. Twenty-eight older women were randomly assigned to a training group (TG) or to a control group (CG). The TG underwent a resistance training program (8 exercises, 2 sets, 10-15 repetitions), while the CG performed stretching exercises (2 sets, 20 s each, 2 nonconsecutive days/week). Both groups performed the intervention for 12 weeks. At baseline and after intervention the subjects were submitted to two sessions: resistance exercise session and control session. In these sessions, BP was obtained in pre and post-sessions. Rest blood pressure were also measure at baseline and after 12 weeks of intervention.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2008

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2008

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
6.6 years until next milestone

First Submitted

Initial submission to the registry

January 20, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 27, 2015

Completed
Last Updated

January 28, 2015

Status Verified

January 1, 2015

Enrollment Period

4 months

First QC Date

January 20, 2015

Last Update Submit

January 26, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • changes in clinic blood pressure

    baseline, 12 weeks

Secondary Outcomes (1)

  • changes in post-exercise blood pressure

    baseline, 12 weeks

Study Arms (2)

Intervention gruop

EXPERIMENTAL

The intervention group was submitted to a resistance training program that consisted of eight exercises performed in two sets of 10 to 15 repetitions, three times per week.

Behavioral: Resistance training

Control group

NO INTERVENTION

The control group performed a stretching training program for the major muscle groups, in sessions of 30 minutes, twice a week

Interventions

Supervised resistance training program was performed on three nonconsecutive days per week at morning period for 12 weeks. The resistance training program included eight exercises in two consecutive sets of 10-15 repetitions until moderate fatigue, except for crunch exercise which was performed on 20 to 30 repetitions without overload. The participants were instructed to perform repetitions at a ratio of 1:2 (concentric and eccentric phases, respectively). Subjects rested for 60- to 90-s between each set and for 2- to 3-min between each exercise. Each subject was individually supervised. Increases of 2-5 % for the upper limb exercises and 5-10 % for the lower limb exercises every time that subjects were able to complete 15 repetitions in both sets.

Intervention gruop

Eligibility Criteria

Age60 Years - 80 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • normotensive female;
  • aged 60-to-80 years old;
  • nonsmokers;
  • without diabetes, cardiac disease or renal dysfunction;
  • not practicing regular physical activity over the six months preceding the beginning of the investigation;
  • being free of any musculoskeletal or other disorders that might affect their ability to participate in the study,
  • should not be taking drugs with inotropic or chronotropic actions;
  • should not be using hormonal replacement therapy;
  • have no restriction for participation in physical exercise, after diagnostic, graded exercise stress test with 12-lead ECG.

You may not qualify if:

  • insufficient attendance to the training sessions (\< 85 % of the total sessions);
  • unavailability of time to perform the evaluations

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Gerage AM, Ritti-Dias RM, do Nascimento MA, Pina FL, Goncalves CG, Sardinha LB, Cyrino ES. Chronic resistance training does not affect post-exercise blood pressure in normotensive older women: a randomized controlled trial. Age (Dordr). 2015 Jun;37(3):63. doi: 10.1007/s11357-015-9801-1. Epub 2015 Jun 6.

MeSH Terms

Interventions

Resistance Training

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Aline M Gerage, Master

    Universidade Estadual de Londrina

    PRINCIPAL INVESTIGATOR
  • Edilson S Cyrino, Doctor

    Universidade Estadual de Londrina

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master student

Study Record Dates

First Submitted

January 20, 2015

First Posted

January 27, 2015

Study Start

February 1, 2008

Primary Completion

June 1, 2008

Study Completion

July 1, 2008

Last Updated

January 28, 2015

Record last verified: 2015-01