NCT02338596

Brief Summary

As clinical and radiographic performance of an ultra-short anatomic cementless stem have been investigated only two randomized controlled studies, well-designed trials should aim for a thorough comparison of the outcomes of ultra-short and conventional cementless stems. The purpose of this study was to compare the outcomes of ultra-short and conventional stems in the same young patients who underwent simultaneous bilateral sequential total hip arthroplasties.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
111

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Jun 2001

Longer than P75 for phase_4

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2001

Completed
12.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2014

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

January 12, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 14, 2015

Completed
Last Updated

January 14, 2015

Status Verified

January 1, 2015

Enrollment Period

12.6 years

First QC Date

January 12, 2015

Last Update Submit

January 13, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Thigh pain

    thigh pain,in visual analog scale 0 to 10.

    10 year after the operation

Secondary Outcomes (1)

  • Harris hip score

    10 year after the operation

Study Arms (2)

Conventional stem

EXPERIMENTAL

total hip replacement operated with conventional stem (Profile; DePuy, Leeds, United Kingdom)

Procedure: Total hip replacement

Ultra-Short stem

ACTIVE COMPARATOR

total hip replacement operated with ultra-short stem (Proxima; DePuy, Leeds, United Kingdom)

Procedure: Total hip replacement

Interventions

1. Simultaneous bilateral sequential total hip arthroplasties under the same anesthetic. 2. Randomization to treatment with an ultra-short or a convnetional cementless stem was accomplished with use of study numbers in sealed envelope, which were opened in the operating room before the skin incision was made. 3. The pore size was 250㎛. A 28-mm-diameter Biolox forte ceramic femoral head (CeramTec AG, Polchingen, Germany) ) was used in all hips. A cementless cup and a 28mm internal-diameter Biolox forte ceramic liner was used in all hips in both groups.

Conventional stemUltra-Short stem

Eligibility Criteria

Age19 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • End stage hip arthritis

You may not qualify if:

  • Age above 50 years old
  • Inflammatory arthritis
  • Coexisting foot or ankle disorder limiting walking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Femur Head NecrosisOsteoarthritis, Hip

Interventions

Arthroplasty, Replacement, Hip

Condition Hierarchy (Ancestors)

OsteonecrosisBone DiseasesMusculoskeletal DiseasesNecrosisPathologic ProcessesPathological Conditions, Signs and SymptomsOsteoarthritisArthritisJoint DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

Arthroplasty, ReplacementArthroplastyOrthopedic ProceduresSurgical Procedures, OperativePlastic Surgery ProceduresProsthesis Implantation

Study Officials

  • Young-Hoo Kim, M.D.

    Professor

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 12, 2015

First Posted

January 14, 2015

Study Start

June 1, 2001

Primary Completion

January 1, 2014

Study Completion

March 1, 2014

Last Updated

January 14, 2015

Record last verified: 2015-01