NCT02336880

Brief Summary

This pilot randomized controlled trial (RCT) aims to test the feasibility and effectiveness of a guided internet-delivered cognitive behavioural therapy intervention in the treatment of cardiac anxiety and fear of body sensations in patients with non-cardiac chest pain. The control group will receive care-as-usual.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

January 8, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 13, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
Last Updated

August 22, 2016

Status Verified

August 1, 2016

Enrollment Period

2 months

First QC Date

January 8, 2015

Last Update Submit

August 19, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cardiac anxiety (Data collection)

    Data collection will be performed before and after the intervention, and 3 and 12 months after the end of the intervention

    12 months

Secondary Outcomes (3)

  • Fear of body sensations (Data collection)

    12 months

  • Depressive symptoms (Data collection)

    12 months

  • Healthcare utilization and costs (Data collection)

    12 months

Study Arms (2)

Intervention group

EXPERIMENTAL

4 weeks guided internet-delivered cognitive behavioural therapy program. The program consists of psychoeducation, exposure to physical activity, and a breathing-based relaxation exercise

Behavioral: Internet-delivered cognitive behavioural therapy

Control group

NO INTERVENTION

Care as usual

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • recurrent chest pain that has been diagnosed as non-cardiac at least twice during last 6 months
  • patients screened positive for avoidance of physical activity due to cardiac anxiety and/or fear of body sensations

You may not qualify if:

  • no regular access to a computer/tablet computer with internet connection
  • language difficulties
  • not able to perform physical activity/exercise test due to physical constraints
  • patients with severe depressive symptoms
  • patients with acute ischemic heart disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Linkoeping University

Linköping, Sweden

Location

Related Publications (1)

  • Mourad G, Stromberg A, Jonsbu E, Gustafsson M, Johansson P, Jaarsma T. Guided Internet-delivered cognitive behavioural therapy in patients with non-cardiac chest pain - a pilot randomized controlled study. Trials. 2016 Jul 26;17(1):352. doi: 10.1186/s13063-016-1491-1.

MeSH Terms

Conditions

Chest PainAnxiety Disorders

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMental Disorders

Study Officials

  • Tiny Jaarsma, Professor

    Linkoeping University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Junior lecturer, PhD-student

Study Record Dates

First Submitted

January 8, 2015

First Posted

January 13, 2015

Study Start

January 1, 2015

Primary Completion

March 1, 2015

Study Completion

June 1, 2016

Last Updated

August 22, 2016

Record last verified: 2016-08

Locations