Impact of Dyspnea on Patients in the Intensive Care Unit
DYSTRESS
Impact of DYSpnea on the ouTcome of Patients Admitted for an Acute RESpiratory Failure in the intenSive Care Unit
1 other identifier
observational
624
1 country
1
Brief Summary
Although pain has been extensively studied in ICU patients, only a few studies have focused on dyspnea, which is experienced by 50% of mechanically ventilated patients. The purpose of the present study is to determine whether dyspnea in intensive care unit patients is associated with a higher length of stay in the ICU and a higher incidence of post traumatic stress disorders.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 8, 2015
CompletedFirst Posted
Study publicly available on registry
January 13, 2015
CompletedStudy Start
First participant enrolled
January 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 13, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2018
CompletedMarch 24, 2021
May 1, 2018
2.3 years
January 8, 2015
March 23, 2021
Conditions
Outcome Measures
Primary Outcomes (2)
ICU length of stay
3 months
incidence of post traumatic stress disorders
3 months
Secondary Outcomes (4)
Anxiety and depression (Hamilton anxiety and depression scale)
3 months
Quality of life (Short-Form 36)
3 months
Pain (Visual Analogic Scale)
3 months
Quality of Sleep (Pittsburgh Scale)
3 months
Eligibility Criteria
The aims of the present multicentre study are 1) to quantify the prevalence of dyspnea in a large population of ICU mechanically ventilated patients, 2) to examine the link between the level of dyspnea and the occurrence of adverse events in the ICU, 3) to determine whether dyspnea in intensive care unit patients is associated with a higher length of stay in the ICU and a higher incidence of post traumatic stress disorder associated symptoms.
You may qualify if:
- Invasive mechanical ventilation in the ICU for \> 24 hours
- Remaining stay in the ICU estimated \> 24 hours
You may not qualify if:
- RASS \<-2 or \>+2
- Delirium (defined according to CAM-ICU)
- Severe cognitive impairment or severe psychiatric disease
- Patient who does not understand French
- Severe depthless
- Age \<18 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Groupe Hospitalier Pitié Salpetriere
Paris, 75013, France
Related Publications (1)
Demoule A, Hajage D, Messika J, Jaber S, Diallo H, Coutrot M, Kouatchet A, Azoulay E, Fartoukh M, Hraiech S, Beuret P, Darmon M, Decavele M, Ricard JD, Chanques G, Mercat A, Schmidt M, Similowski T; REVA Network (Research Network in Mechanical Ventilation). Prevalence, Intensity, and Clinical Impact of Dyspnea in Critically Ill Patients Receiving Invasive Ventilation. Am J Respir Crit Care Med. 2022 Apr 15;205(8):917-926. doi: 10.1164/rccm.202108-1857OC.
PMID: 35061577DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Alesxandre Demoule, MD, PHD
Assistance Publique - Hôpitaux de Paris
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 8, 2015
First Posted
January 13, 2015
Study Start
January 1, 2016
Primary Completion
April 13, 2018
Study Completion
June 1, 2018
Last Updated
March 24, 2021
Record last verified: 2018-05
Data Sharing
- IPD Sharing
- Will not share