NCT02329886

Brief Summary

China, efforts are underway to respond to an unprecedented epidemiologic transition, with soaring rates of cardiovascular disease (CVD), including heart disease and stroke. Yet there may be limitations in translating observations and findings derived from Anglo-based population studies. As such, there is a critical need for population-based studies that provide insight into the risk factors, incidence, and outcomes of CVD in China. The Qingdao Port Health Study is a population-based prospective cohort study of employees of the Qingdao Port Group, China, designed to investigate the burden of CVD and risk factors (e.g., sociodemographic, biological, environmental and clinical factors) associated with disease onset and outcomes.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2013

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2013

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

December 20, 2014

Completed
12 days until next milestone

First Posted

Study publicly available on registry

January 1, 2015

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2016

Completed
Last Updated

August 11, 2016

Status Verified

January 1, 2016

Enrollment Period

2.8 years

First QC Date

December 20, 2014

Last Update Submit

August 10, 2016

Conditions

Keywords

chronic diseasesrisk factorshealth outcomes

Outcome Measures

Primary Outcomes (1)

  • all cause mortality

    The number of all cause death will be collected. The effects of modified risk factors on all cause mortality will be assessed.

    3 year

Secondary Outcomes (3)

  • Heart diseases (defined as myocardial infarction, agina requiring hospitalization and acute/chronic heart failure)

    3 year

  • stroke (defined as ischemic stroke and hemorraghic stroke)

    3 year

  • revascularization (defined as percutaneous coronary intervention, coronary artery bypass grafting and percutaneous transluminal coronary angioplasty)

    3 year

Other Outcomes (4)

  • chronic obstructive pulmonary disease

    3 year

  • chronic renal insufficiency

    3 year

  • chronic liver diseases (defined as cirrhosis and hepatic failure)

    3 year

  • +1 more other outcomes

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Employees and retirees in Qingdao Port Group, Shandong province, China

You may qualify if:

  • All employees and retirees in Qingdao Port Group
  • Aged over 18 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Spatz ES, Jiang X, Lu J, Masoudi FA, Spertus JA, Wang Y, Li X, Downing NS, Nasir K, Du X, Li J, Krumholz HM, Liu X, Jiang L. Qingdao Port Cardiovascular Health Study: a prospective cohort study. BMJ Open. 2015 Dec 9;5(12):e008403. doi: 10.1136/bmjopen-2015-008403.

Biospecimen

Retention: SAMPLES WITH DNA

In 2013, whole blood samples were collected for future genetic studies. And saliva and urine samples were also collected for future analysis.

MeSH Terms

Conditions

Chronic Disease

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Lixin Jiang, MD, PhD

    Chinese Academy of Medical Sciences, Fuwai Hospital

    PRINCIPAL INVESTIGATOR
  • Xiancheng Liu, MD, PhD

    Qingdao Fuwai hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 20, 2014

First Posted

January 1, 2015

Study Start

March 1, 2013

Primary Completion

January 1, 2016

Study Completion

January 1, 2016

Last Updated

August 11, 2016

Record last verified: 2016-01