NCT02313714

Brief Summary

This study intends to treat patient with congestive heart failure that are maximized their pharmacological treatment and at heart transplant wait list. All patients in the treatment arm will receive electric muscular stimulation with a Russian current protocol twice a week for 7 weeks. The outcome will be assessed by the improvement in quality of life and functional capacity.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for not_applicable heart-failure

Timeline
Completed

Started Sep 2012

Typical duration for not_applicable heart-failure

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

November 27, 2013

Completed
1 year until next milestone

First Posted

Study publicly available on registry

December 10, 2014

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

December 10, 2014

Status Verified

December 1, 2014

Enrollment Period

3.2 years

First QC Date

November 27, 2013

Last Update Submit

December 9, 2014

Conditions

Keywords

heart failure, heart transplant, electrical stimulation

Outcome Measures

Primary Outcomes (1)

  • Improvement on distance walked in the six minute walk test

    after 7 weeks of first inttervention

Secondary Outcomes (1)

  • Improvement on quality of life

    7 weeks after first intervention

Study Arms (2)

Neuromuscular stimulation

EXPERIMENTAL

The patients will receive electric muscular stimulation with a Russian current protocol twice a week for 7 weeks.

Device: stimulation wave (2.5 kHz, burst at 50Hz, on/off: 3/9 sec),

Sham Group

PLACEBO COMPARATOR

The patients will receive very low electric muscular stimulation with a no biological or clinical effects

Device: Sham

Interventions

All patients in the treatment arm will receive electric muscular stimulation with a Russian current protocol twice a week for 7 weeks.

Also known as: Neuromuscular stimulation
Neuromuscular stimulation
ShamDEVICE

very low electric muscular stimulation

Sham Group

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients on waiting list for heart transplant

You may not qualify if:

  • patients that won't accept to participate in the protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Campinas

Campinas, São Paulo, 13100000, Brazil

RECRUITING

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Maria Carolina Sacilotto, MsC

    University of Campinas

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Maria Carolina Sacilotto, MsC

CONTACT

Orlando Petrucci, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

November 27, 2013

First Posted

December 10, 2014

Study Start

September 1, 2012

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

December 10, 2014

Record last verified: 2014-12

Locations