Utrecht Coronary Biobank (UCORBIO)
UCORBIO
1 other identifier
observational
3,000
1 country
1
Brief Summary
UCORBIO enrolls patients who undergo coronary angiography (for any indication). The investigators draw blood at the moment of insertion of the procedural arterial catheter. At the moment of inclusion indication, procedural details, risk factor status, medication use and quality of life (RAND-36 and EuroQoL) is assessed. Patients are then followed-up for the occurrence of major adverse cardiovascular events for 5 years. During the follow-up period patients receive a questionnaire every year to check for hospital admissions. The questionnaires at two and five years of follow-up are enriched with quality of life questionnaires (RAND-36 and EuroQoL).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2011
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2011
CompletedFirst Submitted
Initial submission to the registry
November 26, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2014
CompletedFirst Posted
Study publicly available on registry
December 2, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2019
CompletedMarch 6, 2015
March 1, 2015
3.2 years
November 26, 2014
March 5, 2015
Conditions
Outcome Measures
Primary Outcomes (1)
major adverse cardiovascular events [MACE] (Stroke, myocardial infarction, coronary revascularization, death)
Stroke, myocardial infarction, coronary revascularization, death.
5 years
Interventions
Observational study, no intervention.
Eligibility Criteria
All adult (\>18 years) patients who undergo coronary angiography.
You may qualify if:
- Coronary angiography
You may not qualify if:
- Age \< 18 years.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- UMC Utrechtlead
Study Sites (1)
UMC Utrecht
Utrecht, Utrecht, 3508GA, Netherlands
Related Publications (3)
Gijsberts CM, Santema BT, Asselbergs FW, de Kleijn DP, Voskuil M, Agostoni P, Cramer MJ, Vaartjes I, Hoefer IE, Pasterkamp G, den Ruijter HM. Women Undergoing Coronary Angiography for Myocardial Infarction or Who Present With Multivessel Disease Have a Poorer Prognosis Than Men. Angiology. 2016 Jul;67(6):571-81. doi: 10.1177/0003319715604762. Epub 2015 Sep 7.
PMID: 26351289DERIVEDGijsberts CM, Agostoni P, Hoefer IE, Asselbergs FW, Pasterkamp G, Nathoe H, Appelman YE, de Kleijn DP, den Ruijter HM. Gender differences in health-related quality of life in patients undergoing coronary angiography. Open Heart. 2015 Aug 27;2(1):e000231. doi: 10.1136/openhrt-2014-000231. eCollection 2015.
PMID: 26339493DERIVEDGijsberts CM, Gohar A, Ellenbroek GH, Hoefer IE, de Kleijn DP, Asselbergs FW, Nathoe HM, Agostoni P, Rittersma SZ, Pasterkamp G, Appelman Y, den Ruijter HM. Severity of stable coronary artery disease and its biomarkers differ between men and women undergoing angiography. Atherosclerosis. 2015 Jul;241(1):234-40. doi: 10.1016/j.atherosclerosis.2015.02.002. Epub 2015 Feb 4.
PMID: 25670231DERIVED
Biospecimen
Whole blood and EDTA plasma.
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
November 26, 2014
First Posted
December 2, 2014
Study Start
October 1, 2011
Primary Completion
December 1, 2014
Study Completion
December 1, 2019
Last Updated
March 6, 2015
Record last verified: 2015-03