Health Behaviors and Time-of-Day: Older Adult Cognitive Function

NCT02300272 | Completed

• 1 other identifier: IRB201400910
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device. The study period will last 2 weeks. The objectives of the study are to examine the impact of sleep, pain, and circadian rhythm on practice-related learning in older adults at their preferred versus nonpreferred times of day.

Conditions

Alteration of Cognitive Function; Ageing

Keywords

Practice-related learning; Sleep; Pain; Circadian Rhythm; Older Adults

Outcome Measures

Primary Outcomes (1)

• Cognition as assessed by computerized neuropsychological testing

  Cognitive domains include processing speed, immediate memory, delayed memory, and executive function

  Morning and evening completion for 14 days

Study Arms (1)

Typically healthy older adults

Adults 65 years and older with only common late-life medical conditions who will complete a screening that includes a Polysomnograph and assessment that includes Actiwatch.

Device: Polysomnograph; Device: Actiwatch

Interventions

Polysomnograph DEVICE

Participants will be screened for sleep disorders other than chronic insomnia with an in-home overnight sleep monitoring. Monitoring will consist of six electroencephalography (EEG) measures, two electrooculography (EOG), and chin electromyography (EMG) according to standard placements. Other channels will include oxygen saturation level, bilateral anterior tibialis EMG, heart rate (EKG), thoracic strain gauge, and a nasal/oral thermistor. A single night of polysomnography will be collected during the 2 weeks of assessment.

Also known as: AURA Recording System, Grass Technologies

Typically healthy older adults

Actiwatch DEVICE

This device will be worn on the wrist for 14 continuous days to measure limb movements and ambient light.

Also known as: Actiwatch-L, Mini Mitter

Typically healthy older adults

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Typically, healthy older adults

You may qualify if:

• Age of 65 years and older
• Able to read and speak English
• Completion of Morningness-Eveningness Questionnaire

You may not qualify if:

• Significant medical or neurological disorder
• Major psychopathology
• Pain disorder other than fibromyalgia or osteoarthritis
• Sleep disorder other than insomnia
• Cognitive impairment
• Psychotropic or other medications known to alter sleep
• Unable to provide informed consent

Sponsors & Collaborators

• University of Florida: lead

Study Sites (1)

University of Florida

Gainesville, Florida, 32610, United States

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Michael E Robinson, Ph.D.

  University of Florida

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 20, 2014
• First Posted: November 24, 2014
• Study Start: March 1, 2015
• Primary Completion: December 1, 2016
• Study Completion: December 1, 2016
• Last Updated: December 13, 2019

Record last verified: 2019-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)