Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures

NCT02297061 | Completed

• 1 other identifier: TEGHIP
• Study Type: observational
• Target: 180
• Locations: 1 country
• Sites: 1

Brief Summary

Hip fractures are associated with a large hidden blood loss. That is, the total blood loss associated with hip fracture surgery is much greater than that observed intra operatively. There is currently no viable method of identifying patients at risk of transfusion. The on admission haemoglobin level has been shown to be falsely reassuring . We are conducting a study of 200 consecutive hip fracture patients. Thrombelastography (TEG) is taken on admission. The results are blinded to clinicians. Results will be evaluated at the end of the study, comparing intra-operative and total blood losses with the TEG profile of the patient.

Conditions

Hip Fracture; Blood Loss

Keywords

Hip fracture; Thrombelastography; Blood loss

Outcome Measures

Primary Outcomes (1)

• Total blood loss compared to TEG profile on admission

  TEG profiles will be compared to the blood losses of the patients, after completion of the study.

  4 days postoperatively

Secondary Outcomes (2)

• Thrombotic incidences

  90 days after operation

• Mortality

  90 days after operation

Study Arms (1)

TEG group

200 consecutive hip fracture patients, Thrombelastography is performed on admission.

Biological: Thrombelastography analysis (TEG)

Interventions

Thrombelastography analysis (TEG) BIOLOGICAL

TEG analysis is performed on admission

TEG group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Hip fracture patients admitted to Hvidovre University Hospital in the study period.

You may qualify if:

• All hip fracture patients admitted through the emergency room (ER) at Hvidovre University Hospital in the study period.

You may not qualify if:

• Hip fracture patients who are transfered from other wards in the hospital do not go through the ER and are not included.

Sponsors & Collaborators

• Hvidovre University Hospital: lead
• Rigshospitalet, Denmark: collaborator

Study Sites (1)

Hvidovre University Hospital

Hvidovre, 2650, Denmark

Location

MeSH Terms

Conditions

Hip Fractures; Hemorrhage

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Peter T Tengberg, MD

  Hvidovre University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: February 9, 2014
• First Posted: November 21, 2014
• Study Start: December 1, 2013
• Primary Completion: May 1, 2014
• Study Completion: August 1, 2014
• Last Updated: November 21, 2014

Record last verified: 2014-11

Locations

DK (1)