The Effect of Liberal vs. Restrictive Transfusion Strategies on Rehabilitation After Hip Fracture Surgery
1 other identifier
interventional
120
1 country
1
Brief Summary
To examine the effect of two different transfusion regimens on rehabilitation after hip fracture surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_4
Started Jan 2004
Typical duration for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2004
CompletedFirst Submitted
Initial submission to the registry
September 8, 2005
CompletedFirst Posted
Study publicly available on registry
September 13, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2006
CompletedAugust 30, 2011
September 1, 2006
September 8, 2005
August 29, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Postoperative Functional mobility
Restricting factors for functional mobility
Secondary Outcomes (5)
Length of stay
Complications
Dizziness
Exhaustion
Haematoma (leg swelling)
Interventions
Eligibility Criteria
You may qualify if:
- Primary hip fracture
- capable of informed consent
- independently dwelling
- able to ambulate independent of human assistance
- no active heart condition defined as no AMI within 3 months, no unstable angina or present incompensation/pulmonary oedema
- no regular transfusion demand or terminal disease.
You may not qualify if:
- Multiple fractures
- postop. immobilization due to to surgical reasons
- patient refusal to participate in relevant rehabilitation
- reoperation within 4. postoperative day.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hvidovre University Hospitallead
- IMK Fondencollaborator
Study Sites (1)
Hvidovre University Hospital
Hvidovre, 2650, Denmark
Related Publications (3)
Carson JL, Stanworth SJ, Dennis JA, Fergusson DA, Pagano MB, Roubinian NH, Turgeon AF, Valentine S, Trivella M, Doree C, Hebert PC. Transfusion thresholds and other strategies for guiding red blood cell transfusion. Cochrane Database Syst Rev. 2025 Oct 20;10(10):CD002042. doi: 10.1002/14651858.CD002042.pub6.
PMID: 41114449DERIVEDCarson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC. Transfusion thresholds for guiding red blood cell transfusion. Cochrane Database Syst Rev. 2021 Dec 21;12(12):CD002042. doi: 10.1002/14651858.CD002042.pub5.
PMID: 34932836DERIVEDFoss NB, Kristensen MT, Jensen PS, Palm H, Krasheninnikoff M, Kehlet H. The effects of liberal versus restrictive transfusion thresholds on ambulation after hip fracture surgery. Transfusion. 2009 Feb;49(2):227-34. doi: 10.1111/j.1537-2995.2008.01967.x.
PMID: 19389209DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Nicolai B Foss, MD
Hvidovre University Hospital
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 8, 2005
First Posted
September 13, 2005
Study Start
January 1, 2004
Study Completion
March 1, 2006
Last Updated
August 30, 2011
Record last verified: 2006-09