NCT02274142

Brief Summary

The aim of this RCT is to evaluate the survival of different glass ionomer cement in minimally invasive restorations, with different handling characteristics: hand-mixed versus encapsulated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
145

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2014

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

October 15, 2014

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 24, 2014

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
Last Updated

March 11, 2021

Status Verified

March 1, 2021

Enrollment Period

2 years

First QC Date

October 15, 2014

Last Update Submit

March 8, 2021

Conditions

Keywords

dentinal cariesocclusaloccluso-proximal

Outcome Measures

Primary Outcomes (1)

  • Restorations survival

    The survival of restorations will be evaluated over 24 months according to the Frencken and Holmgren (1999) index for occlusal cavities and Roeleveld (2006) for occlusoproximal cavities.

    24 months

Secondary Outcomes (1)

  • Cost-Effectiveness

    24 months

Study Arms (2)

Restorations with Encapsulated material

EXPERIMENTAL

Restorations performed with encapsulated glass ionomer cement (EQUIA - GC Corp). Capsules with glass ionomer will be activated and applied after selective carious tissue removal in primary molars.

Procedure: Restoration with Encapsulated materialDevice: Encapsulated glass ionomer cement (EQUIA - GC Corp).

Restorations with Hand-Mixed material

ACTIVE COMPARATOR

Restorations will be performed with hand-mixed glass ionomer cement (Fuji IX - GC Corp) after selective carious tissue removal in primary molars.

Procedure: Restoration with hand-mixed materialDevice: powder-liquid glass ionomer cement (Fuji IX - GC Corp)

Interventions

restoration with hand-mixed glass ionomer cement

Also known as: Minimally invasive restoration
Restorations with Hand-Mixed material

restoration with encapsulated ionomer cement

Restorations with Encapsulated material
Restorations with Encapsulated material
Restorations with Hand-Mixed material

Eligibility Criteria

Age3 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Children who have sought treatment in the School of Dentistry, University of Sao Paulo;
  • Children between 3 and 10 years old without systemic diseases;
  • Children presenting at least one dentin caries cavity in primary teeth (occlusal or oclusoproximal) with no signs of pulp involvement.

You may not qualify if:

  • Children whose parents did not agree to participate in the study;
  • Children with behavioural issues at the initial exam or who did not assent to participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Sao Paulo

São Paulo, 05508-000, Brazil

Location

Related Publications (1)

  • Oliveira RC, Camargo LB, Novaes TF, Pontes LRA, Olegario IC, Gimenez T, Passaro AL, Tedesco TK, Braga MM, Mendes FM, Raggio DP. Survival rate of primary molar restorations is not influenced by hand mixed or encapsulated GIC: 24 months RCT. BMC Oral Health. 2021 Jul 23;21(1):371. doi: 10.1186/s12903-021-01710-0.

MeSH Terms

Conditions

Dental CariesBites and Stings

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic DiseasesPoisoningChemically-Induced DisordersWounds and Injuries

Study Officials

  • Daniela Raggio, Professor

    University of Sao Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 15, 2014

First Posted

October 24, 2014

Study Start

October 1, 2014

Primary Completion

October 1, 2016

Study Completion

October 1, 2016

Last Updated

March 11, 2021

Record last verified: 2021-03

Locations