Risk Factors for Aortic Dissection in the Chinese Patients
Food and Drug Administration in China
1 other identifier
observational
3,045
0 countries
N/A
Brief Summary
To evaluate epidemiological features of risk factors for aortic dissection (AD) in Chinese patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2011
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedFirst Submitted
Initial submission to the registry
September 20, 2014
CompletedFirst Posted
Study publicly available on registry
October 20, 2014
CompletedOctober 20, 2014
December 1, 2013
Same day
September 20, 2014
October 15, 2014
Conditions
Outcome Measures
Primary Outcomes (1)
Risk factor for aortic dissection in Chinese pupolation
Risk factor
Study Arms (2)
case
Diagnosis of aortic dissection was based on history and physical examination, and confirmed by imaging, visualization at surgery, and/or postmortem examination. According to the Stanford classification system, type A aortic dissection was defined as any dissection that involves the ascending aorta and type B as any that does not. Acute stage was confined to initial 14 days after symptom onset. Simple aortic aneurysm and pseudoaneurysm were excluded. Surgical and endovascular treatments were the main interventions and performed in the case group.
control
As the control group, 2760 patients without AD were obtained from the hospitalized patients in the same period. Types of disease in the control group included congenital heart disease (632), coronary heart disease (467), adult valve disease (375), pulmonary artery hypertension (292), appendicitis (234), pneumonia (197), fracture (189), intestinal polyps (167), gallstone (156), esophagus cancer (51). Patients in the control group were derived from Department of Cardiovascular Surgery, Department of General Surgery, Department of Thoracic Surgery, and Department of Respiration, respectively.
Interventions
Data were collected by a disigned form. Statistic software was used to analyze clinical data.
Eligibility Criteria
Between January, 2011 and December, 2012, we collected 3045 patients with AAD (1668 with type A and 1377 with type B) from 15 major centers in China as the case group. As the control group, 2760 patients without AD were obtained from the hospitalized patients in the same period.
You may qualify if:
- Aortic dissection
- Acute stage
You may not qualify if:
- Simple aortic aneurysm and pseudoaneurysm were excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctor
Study Record Dates
First Submitted
September 20, 2014
First Posted
October 20, 2014
Study Start
January 1, 2011
Primary Completion
January 1, 2011
Study Completion
December 1, 2013
Last Updated
October 20, 2014
Record last verified: 2013-12