Combined Cognitive and Physical Exercises Through Computer Games in Elderly: The LLM Project

NCT02267499 | Completed

• 2 other identifiers: 84171238904
• Study Type: interventional
• Target: 322
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study involved Information and Communication Technologies (ICT) and more specifically computer exercises blended with game activities. It was hypothesized that ICT facilitated, game blended combined cognitive and physical exercise improves global cognition when compared to a control group; and that the number of sessions within exercising participants predict cognitive benefits. In addition, we explored the impact of potential moderators on combined exercise-induced cognitive benefits.

Conditions

Mild Cognitive Impairment; Mild Dementia; Healthy

Keywords

cognitive training; physical training; exercise games; novelty serious games; computer training; mild cognitive impairment; mild dementia; healthy elderly

Outcome Measures

Primary Outcomes (1)

• overall cognition

  Greek versions of the California Verbal Learning Test \[CVLT\], the Digit Span Test and the Trail Making Test \[TMT\] were used to assess cognitive outcomes.

  2 months

Secondary Outcomes (8)

• physical fitness

  2 months

• Episodic memory

  2 months

• working memory

  2 months

• executive function

  2 months

• Quality of Life

  2 months

Study Arms (2)

LLM training

EXPERIMENTAL

Participants use the FitForAll exergaming computer platform as the physical training component (PTC); Participants use the language adapted Version of the BrainFitness Program as the cognitive training component (CTC)

Other: LLM training

Passive Control

NO INTERVENTION

Participants do not receive an intervention serving as passive controls

Interventions

LLM training OTHER

Participants use the FitForAll exergaming computer platform as the physical training component (PTC); Participants use the language adapted Version of the BrainFitness Program as the cognitive training component (CTC)

Also known as: PTC+CTC

LLM training

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• no severe cognitive impairment \[Mini-Mental State Examination, MMSE ≥ 18\], fluent language skills, agreement of a medical doctor and time commitment to the test and exercise protocol.

You may not qualify if:

• concurrent participation in another study, severe physical or psychological disorders which precluded participation in the intervention (i.e., inability to follow instructions), unrecovered neurological disorders such as stroke, traumatic brain injury, unstable medication within the past three months, severe and uncorrectable vision problems, or hearing aid for less than three months.

Sponsors & Collaborators

• Aristotle University Of Thessaloniki: lead
• National and Kapodistrian University of Athens: collaborator
• University of Ulm: collaborator
• Greek Alzheimer's Association and Related Disorders: collaborator

Related Links

• The LLM project web site

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assist. Professor

Study Record Dates

• First Submitted: October 14, 2014
• First Posted: October 17, 2014
• Study Start: November 1, 2010
• Primary Completion: April 1, 2012
• Study Completion: April 1, 2013
• Last Updated: October 20, 2014

Record last verified: 2014-10