NCT02261155

Brief Summary

Changes in sensory thresholds and pain thresholds will be measured with quantitative sensory testing (QST) before and during hypnotic relaxation in healthy volunteers. Hypnotic susceptibility will be assessed before QST. QST data before and during hypnosis will be compared. Observed sensory changes will be evaluated in relation to the assessed hypnotic susceptibility

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Sep 2006

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2007

Completed
7.2 years until next milestone

First Submitted

Initial submission to the registry

September 25, 2014

Completed
15 days until next milestone

First Posted

Study publicly available on registry

October 10, 2014

Completed
Last Updated

October 10, 2014

Status Verified

October 1, 2014

Enrollment Period

11 months

First QC Date

September 25, 2014

Last Update Submit

October 6, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in Quantitative Sensory Testing

    Quantitative Sensory Testing, in detail the following thresholds are included in the testing: Thermal thresholds Cold detection threshold, CDT (°C from baseline 32°C) Warm detection threshold, WDT (°C from baseline 32°C) Thermal sensory limen, TSL (°C) Paradox heat sensation, PHS (x/3) Cold pain threshold, CPT (°C) Heat pain threshold, HPT (°C) Mechanical detection threshold, MDT (mN) Mechanical pain threshold, MPT (mN) Mechanical pain sensitivity, (MPS) Dynamic mechanical allodynia, (DMA) Wind-up, (WUR) Vibration detection threshold, (VDT) (x/8) Pressure pain threshold, (PPT; Pa)

    1 hour

Secondary Outcomes (1)

  • Observed sensory changes during hypnosis compared to hypnotic susceptibility

    1 hour

Study Arms (1)

Hypnosis

OTHER

hypnotic induction followed by relaxation and pleasant imagery

Procedure: Hypnosis

Interventions

HypnosisPROCEDURE

hypnotic Relaxation without specific analgesic suggestion

Also known as: hypnotic relaxation
Hypnosis

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • healthy volunteers

You may not qualify if:

  • health conditions of any Kind
  • inability to read and/ or sign informed consent
  • previous hypnosis experience

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Kramer S, Zims R, Simang M, Ruger L, Irnich D. Hypnotic relaxation results in elevated thresholds of sensory detection but not of pain detection. BMC Complement Altern Med. 2014 Dec 15;14:496. doi: 10.1186/1472-6882-14-496.

MeSH Terms

Interventions

Hypnosis

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Dominik Irnich, Pd Dr. med.

    Multidisciplinary Pain Centre, Department of Anesthesiology, University of Munich

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PD Dr. med.; Head of the Multidisciplinary Pain Centre

Study Record Dates

First Submitted

September 25, 2014

First Posted

October 10, 2014

Study Start

September 1, 2006

Primary Completion

August 1, 2007

Study Completion

August 1, 2007

Last Updated

October 10, 2014

Record last verified: 2014-10