Nationwide Evaluation of Multimodal Rehabilitation in Patients With Chronic Musculoskeletal Pain

NCT02248363 | Unknown

• 1 other identifier: Chronic-pain-effect-prediction
• Study Type: observational
• Target: 6,500
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic pain is a common health problem that causes enormous social costs. A common method for treating patients with chronic pain problems are multimodal rehabilitation (MMR), which consists of a combination of physical exercise, cognitive behavioural therapy and work training coordinated in an interdisciplinary team. Our research aims to evaluate the effectiveness of MMR on health, quality of life, physical activity, return to work and health economics, with the long-term goal of developing MMR. We aim also to evaluate predictive factors for good and bad treatment outcomes in order to better adapt the MMR to the patient. The project is based on patient-reported data from the Swedish Quality Registry for Pain Rehabilitation, which routinely collects data from 40 (2017) Swedish specialist MMR clinics from all parts of the country. We expect increased knowledge of treatment effects and how MMR can be effectively adapted according to the patient's limitations and resources. Our project group is interdisciplinary and is active in nationwide research networks that focus on chronic pain and rehabilitation.

Conditions

Chronic Pain; Widespread Chronic Pain

Keywords

Rehabilitation; Effectiveness; Determinants; Prediction

Outcome Measures

Primary Outcomes (1)

• Health-related quality of life (SF-36)

  The SF-36 is a self-assessed multi-purpose, short-form health survey with only 36 questions. It yields an 8-scale profile of functional health and well-being scores as well as psychometrically-based physical and mental health summary measures and a preference-based health utility index. It is a generic measure, as opposed to one that targets a specific age, disease, or treatment group. Accordingly, the SF-36 has proven useful in surveys of general and specific populations, comparing the relative burden of diseases, and in differentiating the health benefits produced by a wide range of different treatments.

  Change from baseline to post-treatment, and at 12 months follow-up.

Secondary Outcomes (4)

• Multidimensional Pain Inventory (MPI)

  Change from baseline to post-treatment, and at 12 months follow-up.

• Perceived health (EQ-5D)

  Change from baseline to post-treatment, and at 12 months follow-up.

• Pain intensity (numeric rating scale, NRS)

  Change from baseline to post-treatment, and at 12 months follow-up.

• The Hospital Anxiety and Depression Scale, HAD

  Change from baseline to post-treatment, and at 12 months follow-up.

Interventions

Multimodal rehabilitation OTHER

Multimodal rehabilitation (MMR) distinguishes itself as an interdisciplinary-coordinated (e.g., physician, occupational therapist, physiotherapist, and psychologist) intervention using a bio-psycho-social view of chronic pain. The MMR continues over a lengthy period with a common goal and generally includes patient education, supervised physical activity, simulated work training, and cognitive behavioural therapy (CBT). The exact composition of these MMR components depends on initial evaluations of the patients health status and furhter follow-up testing. The MMR interventional components can act independently and interdependently, resulting in combined effects due to known and unknown mechanisms; the effects are intended to be greater than the sum of its components.

Also known as: Multidiciplinary rehabilitation

Eligibility Criteria

• Age: 18 Years - 67 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Included subjects are patients with chronic pain conditions not caused by malignancies (mainly musculoskeletal pain) aged between 18 and 67.

You may qualify if:

• Chronic pain, e.g. long-term neck and back pain or progressed generalized widespread pain that has lasted more than three months
• to 67 yrs old
• Referred to one of the specialist MMR-clinical department in Sweden

You may not qualify if:

• \- Malignancies

Sponsors & Collaborators

• Karolinska Institutet: lead
• The Swedish Research Council: collaborator
• Karolinska Institutet: Doctoral School in Health Care Sciences (NFV): collaborator

Study Sites (1)

Karolinska Institutet

Huddinge, Stockholm County, 79188, Sweden

Location

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Björn Äng, Assoc prof.

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 12 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: September 21, 2014
• First Posted: September 25, 2014
• Study Start: September 1, 2014
• Primary Completion: October 31, 2020
• Study Completion: October 31, 2020
• Last Updated: September 9, 2020

Record last verified: 2020-09

Locations

SE (1)