ADARFEP
Clinical Outcome After Antipsychotic Treatment Discontinuation in Functionally Recovered First-episode Non-affective Psychosis Individuals: A 3-year Follow-up
Sponsor study identifier
interventional
68
1 country
1
Study Start
July 2004
Actual (reported)Primary Completion
February 2014
Actual (reported)Study Completion
July 2014
Actual (reported)This open-label, non-randomized, prospective study will evaluate the risk of symptoms recurrence during the three years after antipsychotic discontinuation in a sample of functionally recovered first-episode patients with schizophrenia spectrum disorder.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2014
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2004
Actual (reported)February 2014
Actual (reported)July 2014
Actual (reported)August 13, 2014
Actual (reported)August 20, 2014
Actual (reported)Relapse rate.
The main outcome was the percentage of relapse/exacerbation in the two groups of patients, discontinuation and maintenance.
At 3 years.
Clinical psychopathology.
At 3 years.
Time to relapse.
At 3 years.
Clinical functionality.
At 3 years.
Antipsychotic treatment discontinuation (DT)
Maintenance antipsychotic treatment (MT)
Withdrawal of antipsychotic medication to stabilized patients.
Maintenance antipsychotic medication to stabilized patients.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
University Hospital Marques de Valdecilla
Santander, Cantabria, 39008, Spain
Mayoral-van Son J, de la Foz VO, Martinez-Garcia O, Moreno T, Parrilla-Escobar M, Valdizan EM, Crespo-Facorro B. Clinical outcome after antipsychotic treatment discontinuation in functionally recovered first-episode nonaffective psychosis individuals: a 3-year naturalistic follow-up study. J Clin Psychiatry. 2016 Apr;77(4):492-500. doi: 10.4088/JCP.14m09540.
Benedicto Crespo-Facorro, Professor
University Hospital Marqués de Valdecilla, IDIVAL, Department of Psychiatry, School of Medicine, University of Cantabria, Santander, Spain. CIBERSAM Centro Investigación Biomédica en Red Salud Mental, Madrid, Spain
68 participants (actual enrollment reported by the registry).
First Submitted
August 13, 2014
First Posted
August 20, 2014
Study Start
July 2004
Actual (reported)Cognitive Remediation Therapy (CRT) in Adolescents With EOS
Contact the study team to confirm eligibility.
Primary Completion
February 2014
Actual (reported)Study Completion
July 2014
Actual (reported)Last Updated
March 14, 2017
Record last verified: 2017-03
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Source: ClinicalTrials.gov.
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