The Effect of Sevofluorane on Wash-out Time in COPD
washout
The Effects of Chronic Obstructive Pulmonary Disease on the Washout Time of Sevofluorane Anesthesia
1 other identifier
observational
60
1 country
1
Brief Summary
COPD (Chronic obstructive disease ) is a condition of respiratory system failure seen occasionally in elderly patients of society. Sevofluorane is a safe, volatile anesthetic used considerably widely all over the world. Because respiratory functions and gas exchange became impaired in COPD patients, the respiratory system excretion/washout of inhalational anesthetic agents can be affected. In our study we aimed to investigate if there is a relation between sevofluorane's washout time and the degree of COPD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Nov 2012
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2012
CompletedFirst Submitted
Initial submission to the registry
July 22, 2014
CompletedFirst Posted
Study publicly available on registry
August 6, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2015
CompletedAugust 6, 2015
August 1, 2015
2.7 years
July 22, 2014
August 5, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
washout time
The time in which sevoflurane MAC level decrease from 0.3 MAC to 0.1MAC and 0,1 MAC to extubation in the patients expiratory gases
second
Secondary Outcomes (1)
extubation time
seconds
Study Arms (2)
Group normal
The patients which have not clinical diagnosis of chronic obstructive lung disease.
Group COPD
The patients which have chronic obstructive lung disease in clinical evaluation
Eligibility Criteria
the study was conducted by reserchers among 60 American Society of Anesthesiologists (ASA) physical status 1 or 2 patients scheduled for orthopedic, urologic and lower limp surgery which performed under general anesthesia .We investigated patientes who have normal pulmonary function and who have chronic obstructive pulmonary disease .We divided into two groups by via questioning and evaluating pulmonary function tests of patients. The patients were 18-60 years old, with body mass index between 22-29
You may qualify if:
- Anesthesiologists (ASA) physical status 1 or 2 patients
- orthopedic, urologic and lower limp surgery which performed under general anesthesia
- normal pulmonary function
- chronic obstructive pulmonary disease
You may not qualify if:
- Cardiac failure
- Hepatic failure
- Renal failure
- Neurologic diseases
- Endocrine diseases
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Duzce Universitylead
Study Sites (1)
Duzce Univercity Medical Fauculty
Düzce, 81620, Turkey (Türkiye)
Related Publications (1)
Adanir T, Atay A, Sencan A, Aksun M, Karahan N. Effect of cigarette smoking on the washout time of sevoflurane anesthesia. BMC Anesthesiol. 2010 Jun 22;10:8. doi: 10.1186/1471-2253-10-8.
PMID: 20569431BACKGROUND
Related Links
Study Officials
- STUDY DIRECTOR
Ilknur Suidiye Seker, Asist. prof.
Duzce University School of Medicine
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant profesor
Study Record Dates
First Submitted
July 22, 2014
First Posted
August 6, 2014
Study Start
November 1, 2012
Primary Completion
August 1, 2015
Study Completion
August 1, 2015
Last Updated
August 6, 2015
Record last verified: 2015-08