Oldest-old Patients Anesthesia in Orthopedic Surgeries

NCT06522178 | Completed

• 1 other identifier: Oldest-old Patient Anesthesia
• Study Type: observational
• Target: 1,356
• Locations: 1 country
• Sites: 1

Brief Summary

Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades. As life expectancy increased, the rate of emergency and elective surgical interventions has also increased in the older age group. Although good health is required to reach an advanced age, over time, organ functions may deteriorate, and some challenges may develop that will negatively affect the balance of homeostasis. Stress, such as trauma or surgery, can cause deterioration in organ functions or aggravation of impaired functions. The risk of developing undesirable events is higher, due to the diminished reserve and function, during anesthesia applied to these patients. There is a limited number of studies in the literature about the relation between the anesthesia technique and morbidity and mortality in oldest old patients operated for orthopedic surgery. In this study, we aimed to analyze the data of the oldest-old patients operated on for orthopedic surgery between 2016-2022, retrospectively, and to investigate the relationship between anesthesia technique and adverse effects including morbidity and mortality.

Conditions

Anesthesia

Outcome Measures

Primary Outcomes (3)

• Mortality

  postoperative mortality

  one month after operation

• Anesthesia Techniques

  Data were also analyzed and compared with groups and between groups according to the applied anesthesia technique (general anesthesia versus regional anesthesia).

  up to 6 hours

• Type of operation

  Orthopedic surgery type

  up to 6 hours

Secondary Outcomes (1)

• Presence and type of comorbidities

  6 month period before operation

Study Arms (2)

Group 1

Group I patients contained those who were between 80 (included) and 89 (included) years of age.

Other: Patient' ages

Group 2

Those who were 90 years of age and above were included in Group II

Other: Patient' ages

Interventions

Patient' ages OTHER

Patients were divided into two groups according to their ages.

Group 1; Group 2

Eligibility Criteria

• Age: 80 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 1356 oldest-old patients underwent orthopedic surgery between January 02 2016 and December 31 2022 in our hospital.

You may qualify if:

• Aged 80 years and above
• Underwent orthopedic surgery

You may not qualify if:

• Those who had the operation with local anesthesia

Sponsors & Collaborators

• Istanbul Medeniyet University: lead

Study Sites (1)

Istanbul Medeniyet University

Istanbul, 34730, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass-Prof

Study Record Dates

• First Submitted: July 22, 2024
• First Posted: July 26, 2024
• Study Start: January 3, 2016
• Primary Completion: December 31, 2022
• Study Completion: January 1, 2024
• Last Updated: July 26, 2024

Record last verified: 2024-07

Locations

TU (1)