NCT02203266

Brief Summary

The purpose of this trial is to discover whether providing feedback to patients from a device that records when and how well a patient uses a Seretide Diskus inhaler will lead to:

  • Improved compliance with prescribed inhaler use
  • Improved technique of inhaler use
  • A reduction in respiratory health related outcomes caused by poor inhaler compliance and usage.
  • An improvement in patient quality of life scores

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
152

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Feb 2014

Typical duration for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2014

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 27, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 29, 2014

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2017

Completed
Last Updated

July 18, 2019

Status Verified

July 1, 2019

Enrollment Period

2.8 years

First QC Date

July 27, 2014

Last Update Submit

July 17, 2019

Conditions

Keywords

Medication AdherencePatient Compliance

Outcome Measures

Primary Outcomes (1)

  • Rate of adherence

    The rate of adherence is the proportion of correctly taken drugs at the correct time relative to the prescribed interval.

    2 months and 6 months

Secondary Outcomes (5)

  • Rescue inhaled medication use

    Six months

  • Rescue antibiotic and/or steroid medication use

    6 months

  • Quality of life

    2 months and 6 months

  • Adherence in the time domain

    Two months and six months

  • Technique adherence

    Two months and six months

Study Arms (3)

Feedback

EXPERIMENTAL

Feedback on the patient's own inhaler use, with personalized information on the patients technique and timing of use of the diskus inhaler as recorded on the INCA device will be provided to patients in the feedback group after 1,2 and 6 months.

Device: Feedback

Demonstration

ACTIVE COMPARATOR

Current best practice - inhaler technique education

Behavioral: Education

Control

NO INTERVENTION

Usual care in the community pharmacy setting

Interventions

FeedbackDEVICE

Feedback on the patient's own inhaler use, with personalized information on the patients technique and timing of use of the diskus inhaler as recorded on the INCA device will be provided to patients in the feedback group after 1,2 and 6 months.

Also known as: INCA Device
Feedback
EducationBEHAVIORAL

Feedback on the patient's own inhaler technique as observed by pharmacist and education to support best use will be provided to patients in the demonstration group after 1,2 and 6 months.

Demonstration

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Must be 18 years old or above
  • Capable of understanding and willing to provide voluntary informed consent before any protocol specific procedures are performed
  • Capable of understanding and complying with the requirements of the protocol, and demonstrating a willingness to attend for all required visits.
  • Able and willing to take inhaled medication.
  • Have a valid prescription for use of a Seretide diskus inhaler or already using a Seretide diskus inhaler.
  • Have a history of regular attendance in the pharmacy in which they are recruited which will be demonstrated by the subject having collected three prescriptions for any medication in that pharmacy in the six months preceeding their recruitment to the study.

You may not qualify if:

  • Patient expressly reports that their physician has indicated that they will not be continuing to receive Seretide over the next 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boots Retail (Ireland) Limited

Dublin, Ireland

Location

Related Publications (1)

  • O'Dwyer SM, MacHale E, Sulaiman I, Holmes M, Hughes C, D'Arcy S, Rapcan V, Taylor T, Boland F, Bosnic-Anticevich S, Reilly RB, Ryder SA, Costello RW. The effect of providing feedback on inhaler technique and adherence from an electronic audio recording device, INCA(R), in a community pharmacy setting: study protocol for a randomised controlled trial. Trials. 2016 May 4;17(1):226. doi: 10.1186/s13063-016-1362-9.

MeSH Terms

Conditions

AsthmaPulmonary Disease, Chronic ObstructiveMedication AdherencePatient Compliance

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Study Officials

  • Richard Costello, Professor

    Royal College of Surgeons in Ireland, Clinical Research Centre, Beaumont Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Richard Costello

Study Record Dates

First Submitted

July 27, 2014

First Posted

July 29, 2014

Study Start

February 1, 2014

Primary Completion

December 1, 2016

Study Completion

January 1, 2017

Last Updated

July 18, 2019

Record last verified: 2019-07

Locations