NCT02192762

Brief Summary

This is a pilot study of a withdrawal regulation training program compared to relaxation training for individuals that are interested in smoking cessation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2011

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

April 10, 2014

Completed
3 months until next milestone

First Posted

Study publicly available on registry

July 17, 2014

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

January 13, 2022

Status Verified

December 1, 2021

Enrollment Period

3.4 years

First QC Date

April 10, 2014

Last Update Submit

December 26, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • Biochemically verified smoking abstinence

    Smoking abstinence will be determined by self-report and confirmed via breath carbon monoxide (CO) analysis. Self-report of no smoking over the past 7 days (7-day point prevalence abstinence) and a CO value of less than 8 parts per million will be indicative of smoking abstinence. Self-report of any smoking over the past 7 days and/or CO values of 8 or greater will be indicative of cigarette use.

    2 months after end-of-treatment

  • Biochemically-verified smoking abstinence

    Smoking abstinence will be determined by self-report and confirmed via breath carbon monoxide (CO) analysis. Self-report of no smoking over the past 7 days (7-day point prevalence abstinence) and a CO value of less than 8 parts per million will be indicative of smoking abstinence. Self-report of any smoking over the past 7 days and/or CO values of 8 or greater will be indicative of cigarette use.

    3 months after end-of-treatment

Secondary Outcomes (2)

  • Withdrawal symptoms

    2 months after end-of-treatment

  • Withdrawal symptoms

    3 months after end-of-treament

Study Arms (2)

Withdrawal regulation training

EXPERIMENTAL

Withdrawal coping skills

Behavioral: Withdrawal regulation training

Relaxation training

ACTIVE COMPARATOR

Relaxation skills instruction

Behavioral: Relaxation training

Interventions

Withdrawal coping skills

Withdrawal regulation training

Relaxation skills instruction

Relaxation training

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men and women at least 19 years of age
  • Reports smoking at least 10 cigarettes per day
  • Must have expired breath carbon monoxide reading of at least eight parts per million
  • Report the intention to quit smoking
  • Reside in the Birmingham area with no plan to relocate outside of the area in the next six months
  • Have access to a telephone for scheduling follow up assessments

You may not qualify if:

  • Inability to speak English
  • Presence of a condition that contraindicates use of transdermal nicotine patch (i.e. angina pectoris, arrhythmia, recent myocardial infarction, allergies to adhesives, serious skin disorders, and current pregnancy or breast feeding)
  • Presence of conditions that might interfere with compliance with protocol or greatly complicate treatment (i.e. current alcohol or other substance dependence, dementia, psychosis, schizophrenia, bipolar disorder, suicidal or homicidal ideation, and any disease acutely life-threatening or so severe that the participant cannot comply with the protocol)
  • Concurrent participation in a formal treatment program for smoking cessation
  • Current use of any pharmacotherapy for smoking cessation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States

Location

MeSH Terms

Conditions

Smoking Cessation

Interventions

Relaxation Therapy

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Peter S Hendricks, PhD

    University of Alabama at Birmingham

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 10, 2014

First Posted

July 17, 2014

Study Start

July 1, 2011

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

January 13, 2022

Record last verified: 2021-12

Locations