NCT01352195

Brief Summary

The primary purpose of this study is smoking cessation. The investigators are conducting a research study to learn how well the information from the program helps participants to quit smoking and remain smoke-free.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,124

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 23, 2009

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

May 10, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 11, 2011

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 18, 2014

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 27, 2014

Completed
Last Updated

November 3, 2022

Status Verified

November 1, 2022

Enrollment Period

5.1 years

First QC Date

May 10, 2011

Last Update Submit

November 2, 2022

Conditions

Keywords

Forever Free

Outcome Measures

Primary Outcomes (1)

  • 7-Day Point-Prevalence Abstinence at Each Follow-up Point

    Time will be measured in months from the start of condition. Potential confounding variables (e.g., group differences in demographic, smoking history, or pharmacotherapy use) will be adjusted for in the model. Pair-wise condition and time interval comparisons will be tested using the generalized score statistics from generalized estimating equations (GEE) models by utilizing the contrast statements.

    30 months per participant

Study Arms (3)

Usual Care (UC)

ACTIVE COMPARATOR

This condition will comprise a single, high quality booklet that is currently in dissemination: NCI's Clearing the Air (NCI, 2003).

Behavioral: Forever Free Booklets

Standard Repeated Mailings (Stand-RM)

ACTIVE COMPARATOR

Stand-RM will be the same 8 Forever Free booklets (edited for cessation) distributed over 12 months as in our preliminary studies.

Behavioral: Forever Free Booklets

Intensive Repeated Mailings (Inten-RM)

ACTIVE COMPARATOR

Inten-RM will add two additional booklets to extend the intervention out to 18 months, plus additional monthly contacts.

Behavioral: Forever Free Booklets

Interventions

Randomized 3-arm design, with 660 smokers recruited into each condition. Assessments will occur at six-month intervals, through 30 months.

Intensive Repeated Mailings (Inten-RM)Standard Repeated Mailings (Stand-RM)Usual Care (UC)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • smoking at least five cigarette per day over the past year
  • not currently enrolled in a face-to-face smoking cessation program
  • able to speak and read English
  • desire to quit smoking, as indicated by a score of at least 5 ("Think I should quit, but not quite ready") on the Contemplation Ladder (Biener \& Abrams, 1991)

You may not qualify if:

  • number of participants from the same street address limited to 1
  • no more than 2 referrals per participant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, 33612, United States

Location

Related Publications (1)

  • Brandon TH, Simmons VN, Sutton SK, Unrod M, Harrell PT, Meade CD, Craig BM, Lee JH, Meltzer LR. Extended Self-Help for Smoking Cessation: A Randomized Controlled Trial. Am J Prev Med. 2016 Jul;51(1):54-62. doi: 10.1016/j.amepre.2015.12.016. Epub 2016 Feb 8.

MeSH Terms

Conditions

Smoking Cessation

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Study Officials

  • Thomas Brandon, Ph.D.

    H. Lee Moffitt Cancer Center and Research Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 10, 2011

First Posted

May 11, 2011

Study Start

January 23, 2009

Primary Completion

February 18, 2014

Study Completion

August 27, 2014

Last Updated

November 3, 2022

Record last verified: 2022-11

Locations