Rewarding Feedback in Motor Learning and Rehabilitation
KFSP-REWARD
Die Auswirkung Von Dopaminergen Belohnungsreizen Auf Das Lernen Einer Motorischen Fertikgeit Bei Gesunden Probanden "Effects of Dopaminergic Reward on Motor Skill Learning in Healthy Subjects"
1 other identifier
interventional
45
1 country
1
Brief Summary
The effect of rewarding vs. non-rewarding feedback on acquisition of a motor skill is investigated in a single blinded parallel group design. Reward consists of performance dependent monetary reward, or of knowledge of performance in selected (above average) trials. The investigators hypothesize improved motor skill learning and higher involvement of the dopaminsrgic system under rewarding vs. non-rewarding conditions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2014
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
June 30, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2014
CompletedFirst Posted
Study publicly available on registry
July 14, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2016
CompletedMay 2, 2016
April 1, 2016
6 months
June 30, 2014
April 29, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Motor skill learning using an arc pointing task
temporal and spacial precision in an arc pointing task will be assessed using 5 different movement speeds during the above mentioned time periods before and after a specific motor learning programm. Learning will be assessed as change from pre-training to post training
about 10 minutes pre-training, about 10 min post training, about 24h post training
Study Arms (3)
Intrinsic reward
ACTIVE COMPARATORFeedback about good performance
Intrinsic and extrinsic reward
EXPERIMENTALFeedback about good performance + money
Intrinsic reward (average performance)
EXPERIMENTALFeedback about random selection of trials
Interventions
Eligibility Criteria
You may qualify if:
- neurologically healthy
- right handed
You may not qualify if:
- Contraindications against magnetic resonance imaging
- pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Kai Lutz, PhDlead
- University of Zurichcollaborator
Study Sites (1)
Cereneo, Center For Rehabilitation and Neurology
Vitznau, Canton of Lucerne, 6354, Switzerland
Related Publications (1)
Widmer M, Ziegler N, Held J, Luft A, Lutz K. Rewarding feedback promotes motor skill consolidation via striatal activity. Prog Brain Res. 2016;229:303-323. doi: 10.1016/bs.pbr.2016.05.006. Epub 2016 Jul 7.
PMID: 27926445DERIVED
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Scientific Director
Study Record Dates
First Submitted
June 30, 2014
First Posted
July 14, 2014
Study Start
January 1, 2014
Primary Completion
July 1, 2014
Study Completion
April 1, 2016
Last Updated
May 2, 2016
Record last verified: 2016-04