HIT in the Healthy Elderly Population

NCT02167191 | Completed

• 1 other identifier: HIT
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery. Conversely, unfit patients have a significantly higher morbidity and mortality after surgery and a longer inpatient stay. This will become increasingly important in an aging population as baseline fitness generally declines with age. One method of improving cardiovascular fitness is by using low intensity endurance training programmes, a disadvantage of these it that they can take several months to show improvement. High intensity interval training (HIT) programmes that use short episodes of high intensity exercise have also been shown to improve fitness. These HIT programmes have also shown improvement in functional capacity and quality of life in patients with chronic disease. An advantage of HIT is that improvements in fitness may occur in a shorter time than traditional endurance training. It is also known that HIT can give superior gains over endurance training. The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by a 2ml/kg/min increase in VO2peak, can be achieved within 31 days via a HIT programme, in a group of healthy elderly volunteers. As a secondary aim we will assess whether this programme would be acceptable to the group studied, through determination of subject compliance and adherence to the training programme.

Conditions

Interval Training; Pre Operative Exercise; Prehabilitation; Elderly

Outcome Measures

Primary Outcomes (1)

• VO2 peak

  31 days

Study Arms (1)

HIT

EXPERIMENTAL

High intensity interval training sessions on an cycle ergometer

Behavioral: HIT

Interventions

HIT BEHAVIORAL

12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

HIT

Eligibility Criteria

• Age: 60 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Good health
• Male and female
• years old

You may not qualify if:

• Uncontrolled hypertension (BP \> 140/100)
• Angina
• Heart failure (NYHA class III/IV)
• Cardiac arrthymias
• Right to left cardiac shunt
• Recent cardiac event
• Previous stroke/TIA
• Aneurysm (large vessel or intracranial)
• Severe respiratory disease including pulmonary hypertension
• COPD/asthma with an FEV1 less than 1.5 l

Sponsors & Collaborators

• University of Nottingham: lead

Study Sites (1)

University of Nottingham

Derby, Derbyshire, DE22 3DT, United Kingdom

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 16, 2014
• First Posted: June 18, 2014
• Study Start: February 1, 2014
• Primary Completion: July 1, 2014
• Study Completion: August 1, 2014
• Last Updated: October 1, 2015

Record last verified: 2015-09

Locations

GB (1)