NCT02147522

Brief Summary

Study Hypotheses (Ho) and Research Questions (RQ):

  • Ho1. AHH will significantly improve patient depression treatment acceptance/adherence and depression symptoms vs UC at 6 and 12 months post-baseline.
  • Ho2. A Helping Hand (AHH) will significantly improve and sustain patient self-care management in Self-Efficacy for Managing Chronic Disease (SEMCD) and Quality of Life vs UC at 6 and 12 months post-baseline.
  • RQ1. What is the association between depression symptoms and concurrent chronic illness self-care management over time by group?
  • RQ2. Will AHH reduce hospitalizations and Emergency Room visits and improve clinic appointment-keeping?
  • RQ3. Will patient care satisfaction and reported barriers to self-care management vary by study group?
  • RQ4. What factors are identified via qualitative assessments of patients, promotoras, Department of Health Services (DHS) medical and social work providers, and DHS clinic/organizational leadership regarding satisfaction with, sustainable uptake of, and suggested modifications of the AHH promotora delivery model?
  • RQ5. What potential technology applications would enhance promotoras delivering patient-centered self-care training and resource navigation, communicating and integrating care with DHS, and disseminating AHH?

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
348

participants targeted

Target at P75+ for not_applicable depression

Timeline
Completed

Started Oct 2013

Typical duration for not_applicable depression

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2013

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

May 19, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 26, 2014

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2016

Completed
11 months until next milestone

Results Posted

Study results publicly available

August 2, 2017

Completed
Last Updated

August 2, 2017

Status Verified

April 1, 2017

Enrollment Period

2.9 years

First QC Date

May 19, 2014

Results QC Date

November 30, 2016

Last Update Submit

April 20, 2017

Conditions

Keywords

community health workerpromotorasself-care behaviors activationdepressionlow-income patientssafety-net care

Outcome Measures

Primary Outcomes (1)

  • Response Rate - 50 Percent or Greater Reduction in Patient Health Survey-9 (PHQ-9) Score Since Baseline

    The PHQ-9, which establishes provisional depressive disorder diagnosis as well as grades depressive symptom severity, will be obtained from all study subjects at recruitment and during the four waves of data collection (up to 12 months). The PHQ-9 scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day), with possible scores ranging from 0 to 27, with cut points of 5,10,15, and 20 representing the thresholds for mild, moderate, moderately severe, and severe depression. A validated Spanish version of the PHQ-9 will be used. Clinically meaningful improvement of depressive symptoms was assessed as a ≥50% score reduction since baseline assessment.

    6- and12-month follow-ups

Secondary Outcomes (1)

  • Change From Baseline in MOS Short-Form Health Survey Physical Component Summary (PCS)

    baseline, 6- and 12-month follow-ups

Other Outcomes (1)

  • Change From Baseline in Self-Efficacy for Managing Chronic Disease (SEMCD) Score

    baseline, 6- and 12-month follow-ups

Study Arms (2)

A Helping Hand (AHH)

EXPERIMENTAL

Participants receive DHS-PCMH usual care from their respective county health clinic providers plus the AHH intervention provided by study promotoras. AHH intervention includes 6 weekly in-person or via-telephone intervention sessions followed by 3 monthly telephone booster sessions aimed at reducing the burden and strain on patients, families, and care providers by assessing, enhancing, and facilitating patient depression and co-morbid illness self-care management, and activating patient communication with clinic medical providers.

Behavioral: Self-care management

Usual Care (UC)

NO INTERVENTION

Participants receive DHS Patient Centered Medical Home (PCMH) clinic team usual care from their respective county health clinic providers. PCMH model has available DHS medical providers and social workers for depression care and refer patients when indicated to community mental health clinics. Problem-Solving Therapy (PST) is available in some of participating clinics.

Interventions

AHH behavioral intervention is provided by promotoras

A Helping Hand (AHH)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \>=18 years, have a phone, meet PHQ-9 score of 10 or more, and have concurrent diabetes, CHD, or HF.

You may not qualify if:

  • current suicidal ideation,inability to speak either English or Spanish fluently, a score of 2 or greater on the CAGE 4M alcohol assessment,recent use of lithium or antipsychotic medication, and cognitive impairment precluding informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

El Monte Comprehensive Health Center

El Monte, California, 91731, United States

Location

H. Claude Hudson Comprehensive Health Center

Los Angeles, California, 90007, United States

Location

Edward R. Roybal Comprehensive Health Center

Los Angeles, California, 90022, United States

Location

Related Publications (3)

  • Oh H, Ell K. Associations Between Changes in Depressive Symptoms and Social Support and Diabetes Management Among Low-Income, Predominantly Hispanic Patients in Patient-Centered Care. Diabetes Care. 2018 Jun;41(6):1149-1156. doi: 10.2337/dc17-2000. Epub 2018 Mar 27.

  • Ell K, Aranda MP, Wu S, Oh H, Lee PJ, Guterman J. Promotora assisted depression and self-care management among predominantly Latinos with concurrent chronic illness: Safety net care system clinical trial results. Contemp Clin Trials. 2017 Oct;61:1-9. doi: 10.1016/j.cct.2017.07.001. Epub 2017 Jul 3.

  • Ell K, Aranda MP, Wu S, Oh H, Lee PJ, Guterman J. Promotora assisted depression care among predominately Hispanic patients with concurrent chronic illness: Public care system clinical trial design. Contemp Clin Trials. 2016 Jan;46:39-47. doi: 10.1016/j.cct.2015.11.012. Epub 2015 Nov 17.

MeSH Terms

Conditions

DepressionDiabetes MellitusHeart Diseases

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesCardiovascular Diseases

Limitations and Caveats

1\) patients lost follow up in intervention visits, outcome interviews; 2) community health workers activated in DHS-PCMH at the same time the AHH trial started; 3) reliance on self-reported outcomes while DHS medical records system update was delayed

Results Point of Contact

Title
Kathleen Ell, DSW, Principle Investigator
Organization
USC Suzanne Dworak-Peck School of Social Work

Study Officials

  • Kathleen Ell, DSW

    USC Suzanne Dworak-Peck School of Social Work

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 19, 2014

First Posted

May 26, 2014

Study Start

October 1, 2013

Primary Completion

September 1, 2016

Study Completion

September 1, 2016

Last Updated

August 2, 2017

Results First Posted

August 2, 2017

Record last verified: 2017-04

Data Sharing

IPD Sharing
Will not share

Locations