The Effects of Resistance Training Intensity on Muscular Hypertrophy and Strength in Young, Resistance Trained Men
Sponsor study identifier
interventional
50
1 country
2
Study Start
May 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2015
Actual (reported)Study Completion
March 2016
Actual (reported)When practicing weightlifting regularly the body makes new proteins within the muscle. These new proteins can increase the size of the cells within the muscle to make them larger, a process called hypertrophy. The common convention surrounding gains in skeletal muscle size and strength is that heavy weights are needed. In contrast, lifting lighter weights are thought to be required to induce muscular endurance and not to promote growth. However, it has previously been shown in untrained men that lifting lighter weights results in similar gains in muscle mass and strength as lifting heavier weights. The purpose of this study is to examine how performing resistance training of different intensities (light or heavy weights) affects the degree of muscle growth and strength gain in individuals who are already resistance training. This information will be valuable when designing exercise protocols for increasing muscle size and strength at all ages, or in individuals returning from injury, as a way to stimulate muscle growth and promote strength gains without the need to lift heavy weights.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 2016
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 7, 2014
Actual (reported)May 2014
Date type not reportedThis date has not been verified as actual or estimated.
May 15, 2014
Actual (reported)December 2015
Actual (reported)March 2016
Actual (reported)Muscle Volume
Change from baseline at 12 weeks Measured via 4 compartment model
0 weeks (baseline) and 12 weeks
Gene expression
0 weeks (baseline) and 12 weeks
Training at 30% 1RM
Training at 80% 1RM
Participant exercises using a protocol tailored at 30% of their 1RM
Participant exercises using a protocol tailored at 80% of their 1RM
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Exercise Metabolism Research Laboratory, McMaster Univeristy
Hamilton, Ontario, L8S 4K1, Canada
McMaster University
Hamilton, Ontario, L8S 4L8, Canada
Morton RW, Oikawa SY, Wavell CG, Mazara N, McGlory C, Quadrilatero J, Baechler BL, Baker SK, Phillips SM. Neither load nor systemic hormones determine resistance training-mediated hypertrophy or strength gains in resistance-trained young men. J Appl Physiol (1985). 2016 Jul 1;121(1):129-38. doi: 10.1152/japplphysiol.00154.2016. Epub 2016 May 12.
Stuart Phillips, Ph.D.
McMaster University
50 participants (actual enrollment reported by the registry).
First Submitted
April 7, 2014
First Posted
May 15, 2014
Study Start
May 2014
Date type not reportedThis date has not been verified as actual or estimated.
Delivra Topical Creatine Combined With Oral Creatine for Improving Muscular Power
Contact the study team to confirm eligibility.
Primary Completion
December 2015
Actual (reported)Study Completion
March 2016
Actual (reported)Last Updated
March 19, 2018
Record last verified: 2016-03
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: