NCT02300636

Brief Summary

This study investigates different resistive co-contraction trainings effect on knee strength recovery after ACL reconstruction. Participants will be divided into three groups. Group 1 will receive standard ACL rehabilitation with 8 week co-contraction training in open kinetic chain position, Group 2 will receive standard ACL rehabilitation with 8 week co-contraction training in open kinetic chain position and Group 3 (control group) will only receive standard ACL rehabilitation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2014

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

November 21, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 25, 2014

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
Last Updated

March 18, 2015

Status Verified

March 1, 2015

Enrollment Period

1.1 years

First QC Date

November 21, 2014

Last Update Submit

March 17, 2015

Conditions

Keywords

Knee jointMuscle strengthanterior cruciate ligament

Outcome Measures

Primary Outcomes (1)

  • knee muscle strength recovery

    isometric, concentric and eccentric strength

    8 weeks

Secondary Outcomes (1)

  • hamstring quadriceps ratio

    6 months

Study Arms (3)

Training: open kinetic

EXPERIMENTAL

Co-contraction training in open kinetic chain position 8 weeks, 3 days in a week

Other: Training

Training: closed kinetic

EXPERIMENTAL

Co-contraction training in closed kinetic chain position 8 weeks, 3 days in a week

Other: Training

Training: Standard ACL rehabilitation

ACTIVE COMPARATOR

Standard ACL rehabilitation 8 weeks, 3 days in a week

Other: Training

Interventions

Co-contraction training at 60 knee flexion angle by using isokinetic dynamometer

Training: open kinetic

Eligibility Criteria

Age17 Years - 40 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • ACL reconstruction with hamstring autograft
  • starting PT program within one week after surgery

You may not qualify if:

  • Revision surgery
  • serious cartilage damage and/or cartilage repair
  • ACL reconstruction with allograft and patellar tendon graft
  • Having systemic and/or neurological problems

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University, Department of Physiotherapy and Rehabilitation

Ankara, 06100, Turkey (Türkiye)

Location

Related Publications (7)

  • Cho SH, Bae CH, Gak HB. Effects of closed kinetic chain exercises on proprioception and functional scores of the knee after anterior cruciate ligament reconstruction. J Phys Ther Sci. 2013 Oct;25(10):1239-41. doi: 10.1589/jpts.25.1239. Epub 2013 Nov 20.

    PMID: 24259766BACKGROUND
  • Lobb R, Tumilty S, Claydon LS. A review of systematic reviews on anterior cruciate ligament reconstruction rehabilitation. Phys Ther Sport. 2012 Nov;13(4):270-8. doi: 10.1016/j.ptsp.2012.05.001. Epub 2012 Jun 7.

    PMID: 23068905BACKGROUND
  • Begalle RL, Distefano LJ, Blackburn T, Padua DA. Quadriceps and hamstrings coactivation during common therapeutic exercises. J Athl Train. 2012 Jul-Aug;47(4):396-405. doi: 10.4085/1062-6050-47.4.01.

    PMID: 22889655BACKGROUND
  • Glass R, Waddell J, Hoogenboom B. The Effects of Open versus Closed Kinetic Chain Exercises on Patients with ACL Deficient or Reconstructed Knees: A Systematic Review. N Am J Sports Phys Ther. 2010 Jun;5(2):74-84.

    PMID: 21589664BACKGROUND
  • Tagesson S, Oberg B, Good L, Kvist J. A comprehensive rehabilitation program with quadriceps strengthening in closed versus open kinetic chain exercise in patients with anterior cruciate ligament deficiency: a randomized clinical trial evaluating dynamic tibial translation and muscle function. Am J Sports Med. 2008 Feb;36(2):298-307. doi: 10.1177/0363546507307867. Epub 2007 Oct 16.

    PMID: 17940146BACKGROUND
  • Biscarini A, Benvenuti P, Botti FM, Brunetti A, Brunetti O, Pettorossi VE. Voluntary enhanced cocontraction of hamstring muscles during open kinetic chain leg extension exercise: its potential unloading effect on the anterior cruciate ligament. Am J Sports Med. 2014 Sep;42(9):2103-12. doi: 10.1177/0363546514536137. Epub 2014 Jun 10.

    PMID: 24918112BACKGROUND
  • Palmieri-Smith RM, McLean SG, Ashton-Miller JA, Wojtys EM. Association of quadriceps and hamstrings cocontraction patterns with knee joint loading. J Athl Train. 2009 May-Jun;44(3):256-63. doi: 10.4085/1062-6050-44.3.256.

    PMID: 19478837BACKGROUND

MeSH Terms

Conditions

Muscle Weakness

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms

Study Officials

  • GULCAN HARPUT, MSc

    Hacettepe University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PT, MSc

Study Record Dates

First Submitted

November 21, 2014

First Posted

November 25, 2014

Study Start

February 1, 2014

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

March 18, 2015

Record last verified: 2015-03

Locations