NCT02133027

Brief Summary

Objective:To explore the role of the right portal pedicle and Rouviere's sulcus as an anatomic landmark in laparoscopic cholecystectomy. Methods:The investigators are going to select 60 patients intending to perform Laparoscopic cholecystectomy from April 2014 to April 2015.Check out the presence of the right portal pedicle and Rouviere's sulcus during the surgery and divide into the experimental group and the control group.Experimental group operated in Laparoscopic cholecystectomy with the guide of Rouviere's sulcus while the Control group operated with the traditional way. Research hypothesis:Compare the differences between the Experimental group and the Control group in bile duct injury rate,complication rate,blood loss,operative time ,conversion rate and hospital stay.It is supposed that the results of Experimental group are superior to the control group,difference is statistically significant(P\<0.05). So the investigators can draw the conclusion that the anatomy method with the guide of right portal pedicle and Rouviere's sulcus is useful in laparoscopic cholecystectomy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2014

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2014

Completed
27 days until next milestone

First Submitted

Initial submission to the registry

April 28, 2014

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 7, 2014

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2015

Completed
Last Updated

May 7, 2014

Status Verified

May 1, 2014

Enrollment Period

1 year

First QC Date

April 28, 2014

Last Update Submit

May 3, 2014

Conditions

Keywords

Laparoscopic cholecystectomy

Outcome Measures

Primary Outcomes (1)

  • complication rate

    biliary injury,artery injury etc.

    one month

Secondary Outcomes (1)

  • conversion rate

    From date of randomization until the date of first documented progression ,assessed up to 12 months

Other Outcomes (2)

  • hospital stay

    participants will be followed for the duration of hospital stay, an expected average of 1 weeks

  • blood loss

    From date of randomization until the date of first documented progression ,assessed up to 12 months

Study Arms (2)

Rouviere's Sulcus

EXPERIMENTAL

Rouviere's sulcus is a 2 to 5 cm sulcus running to the right of the liver hilum anterior to the caudate process and usually containing the right portal triad or its branches.Dissection may be started safely by division of the peritoneum immediately ventral to the sulcus and continued in a triangle bounded by the liver surface, the neck of the gallbladder and the plane of the sulcus.

Procedure: Rouviere's sulcusDevice: surgical instruments

traditional anatomy method

OTHER

Ratcheted grasper is inserted through the lateral 5-mm port to retract the gallbladder fundus in cephalad fashion. An atraumatic grasper is inserted through the middle 5-mm port to retract the gallbladder infundibulum laterally, exposing the anteromedial aspect of the triangle of Calot.

Device: surgical instruments

Interventions

Dissection may be started safely by division of the peritoneum immediately ventral to the sulcus and continued in a triangle bounded by the liver surface, the neck of the gallbladder and the plane of the sulcus.

Rouviere's Sulcus

surgical instruments used in the laparoscopic cholecystectomy,such as ratcheted grasper,atraumatic grasper ,scissors.

Also known as: Operating apparatus
Rouviere's Sulcustraditional anatomy method

Eligibility Criteria

Age20 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Symptomatic gallstones
  • Gallstones\>3cm in diameter
  • Fulfilled gallstones
  • Acute or chronic cholecystitis
  • Acalculous cholecystitis
  • Gallbladder polyps \>10mm in diameter
  • Symptomatic gallbladder polyps
  • Gallbladder stones associated with polyps
  • Porcelain gallbladder
  • Gallstone pancreatitis

You may not qualify if:

  • Suspicion of gallbladder cancer
  • General condition is poor,inability to tolerate gallbladder cancer
  • Important organ dysfunction
  • Severe abdominal cavity adhesion
  • Bleeding disorders,blood coagulation dysfunction
  • Acute cholangitis with serious complications(gallbladder empyema,gangrene,perforation)
  • Acute cholangitis
  • Pregnancy(first or third trimester)
  • Abdominal dysfunction or peritonitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Hepatobiliary (I),Zhujiang Hospital

Guangzhou, Guangdong, 510280, China

RECRUITING

Related Publications (1)

  • Dahmane R, Morjane A, Starc A. Anatomy and surgical relevance of Rouviere's sulcus. ScientificWorldJournal. 2013 Nov 6;2013:254287. doi: 10.1155/2013/254287. eCollection 2013.

    PMID: 24319350BACKGROUND

MeSH Terms

Conditions

GallstonesCholecystitisPolyps

Interventions

Surgical Instruments

Condition Hierarchy (Ancestors)

CholelithiasisBiliary Tract DiseasesDigestive System DiseasesCholecystolithiasisGallbladder DiseasesCalculiPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Surgical EquipmentEquipment and Supplies

Study Officials

  • Fan yi fang, Prof.

    Department of Hepatobiliary Surgery(I),Zhujiang Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Wang li qing, Doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2014

First Posted

May 7, 2014

Study Start

April 1, 2014

Primary Completion

April 1, 2015

Study Completion

April 1, 2015

Last Updated

May 7, 2014

Record last verified: 2014-05

Locations