Exercise and Repetitive Diving
The Impact of Predive Exercise on Repetitive SCUBA Diving
1 other identifier
interventional
16
2 countries
2
Brief Summary
SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives. 16 divers in 2 groups each completed 6 dives. One group completed 3 control dives followed by 5 days rest then 3 dives preceded by exercise. The other group completed the opposite protocol. Flow-mediated dilation (FMD) data and blood for MP analysis was collected before and after each dive. VGE were monitored via transthoracic echocardiography 30, 60, and 90 min after surfacing. Exercise before diving consisted of 60 min running outdoors including 8x4 min intervals at 90% VO2max effort.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2013
Shorter than P25 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
April 16, 2014
CompletedFirst Posted
Study publicly available on registry
April 21, 2014
CompletedApril 21, 2014
April 1, 2014
1 month
April 16, 2014
April 16, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in circulating microparticle counts
Change in circulating microparticle counts measured pre and post SCUBA diving following 6 dives spaced over 12 days
2 weeks
Study Arms (2)
Control dives 1st
EXPERIMENTALSubjects in this group complete the first 3 dives as control dives and the second 3 dives preceded by aerobic exercise
Predive exercise 1st
EXPERIMENTALSubjects complete the first 3 dives preceded by the intervention of aerobic exercise and the second 3 with no exercise as control dives
Interventions
60 min of aerobic intervals completed prior to SCUBA diving
Eligibility Criteria
You may qualify if:
- Certified SCUBA diver
- Certified to dive by experienced Medical evaluator
- Must be able to run continuously for 45 min
You may not qualify if:
- Prior diagnosis of decompression sickness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Splitlead
- University of Marylandcollaborator
Study Sites (2)
University of Maryland
Baltimore, Maryland, 21201, United States
University of Split School of Medicine
Split, 21000, Croatia
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Zeljko Dujic, MD, PhD
University of Split, School of Medicine
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor Zeljko Dujic MD, PhD, Director of Department of Physiology
Study Record Dates
First Submitted
April 16, 2014
First Posted
April 21, 2014
Study Start
October 1, 2013
Primary Completion
November 1, 2013
Study Completion
January 1, 2014
Last Updated
April 21, 2014
Record last verified: 2014-04