Study Stopped
Dr Zhu, collaborator and the inventor of the photoacoustic system, is leaving the institution and it is not feasible to conduct the study without the machine.
Photoacoustic Imaging of the Ovary
2 other identifiers
interventional
2
1 country
1
Brief Summary
The purpose of this study is to develop technology to image the ovaries in order to better evaluate ovarian disease and to study how these experimental imaging techniques might work together or separately to improve our ability to detect ovarian cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable ovarian-cancer
Started Mar 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2014
CompletedFirst Submitted
Initial submission to the registry
April 7, 2014
CompletedFirst Posted
Study publicly available on registry
April 10, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedResults Posted
Study results publicly available
March 13, 2018
CompletedMarch 13, 2018
November 1, 2017
2.2 years
April 7, 2014
November 17, 2017
March 8, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
To Measure Photoacoustic Imaging (PAI)/Ultrasound Signature From Ovaries Prior to Surgery Using the Ratio of Deoxy/Oxy Hb
To develop a method of analyzing PAI ovarian tissue images measuring oxy and deoxy hemoglobin as well as the ratio of deoxy/oxy Hb to recognize the presence of ovarian abnormalities and compare changes seen with ultrasound to changes seen with PAI.
5 years
Secondary Outcomes (1)
Pathologic Diagnosis and in Vivo Imaging
5 years
Study Arms (1)
PAI/ultrasound Diagnostic Group
EXPERIMENTALThese patients will include women who are at risk for ovarian cancer and wish to undergo prophylactic oophorectomy, or who have an ovarian mass suggestive of a malignancy and are counseled to undergo oophorectomy.
Interventions
These patients will include women who are at risk for ovarian cancer and wish to undergo prophylactic oophorectomy, or who have an ovarian mass suggestive of a malignancy and are counseled to undergo oophorectomy.
Eligibility Criteria
You may qualify if:
- All patients, twenty one years or older, referred to the University of Connecticut for conditions necessitating oophorectomy.
- Patients cannot be pregnant or wish to become pregnant.
- Willingness to participate in the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- UConn Healthlead
- National Cancer Institute (NCI)collaborator
Study Sites (1)
UConn Health
Farmington, Connecticut, 06032, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr.Molly Brewer
- Organization
- UConn Health
Study Officials
- PRINCIPAL INVESTIGATOR
Molly Brewer, MD
UConn Health
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, Obstetrics and Gynecology
Study Record Dates
First Submitted
April 7, 2014
First Posted
April 10, 2014
Study Start
March 1, 2014
Primary Completion
May 1, 2016
Study Completion
May 1, 2016
Last Updated
March 13, 2018
Results First Posted
March 13, 2018
Record last verified: 2017-11