NCT02095457

Brief Summary

Scientific Background: Inherent gaps exist between the worlds of research and clinical therapy, especially in mental-health systems. Developed as an important strategy aimed to bridge them, widening efforts worldwide have implemented Routine Outcome Monitoring (ROM), a method devised for systematic ongoing quantitative measurements used in diverse clinical practices, from psychotherapies to psychiatric management. The efficacy of this approach has been repeatedly demonstrated in various measures, such as satisfaction with treatment by patients and therapists, lower drop-out rates, symptomatic benefits, and more. Objectives: The aim of the current study is to test the feasibility and the clinical benefits of implementation of a Routine Outcome Monitoring System in a public clinical center, as a pioneering project in Israel, at the "Shalvata" Mental Health Center. Working Hypotheses: Incorporation of a ROM system in routine clinical practice is hypothesized to improve patients' and therapists' overall satisfaction, allow for early detection and intervention in therapeutic raptures, decrease drop-out rates, and improve various clinical outcome measures. Methods: The suggested study is a two-stage (implementation and intervention) open trial. 900 new outpatients in 'Shalvata' clinics will be recruited and randomized to intervention (ROM) and control groups. Assessment questionnaires will be filled periodically using 'CORE-NET', a computerized system enabling repeated measurements and feedback in a user-friendly and efficient manner. Data Analysis: The evaluation of the differential influence of monitoring processes on overall efficiency as compared to control group will be tested using Multiple Analysis of Variance (MANOVA). The predictive value of possible variables on process and outcome of therapy will be assessed using stratified regression analyses. The possible causal effects between specific lagged variables will be assessed using Hierarchical Linear Modeling and Time Series Analysis. Contribution: This pioneering study is the first in Israel to offer a routine systematic evaluation of therapeutic processes, as well as assessing its clinical effects. Consequently, a large and meaningful data-set will emerge, enabling significant enrichment of our evidence-based understanding of therapeutic processes.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
900

participants targeted

Target at P75+ for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 19, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 24, 2014

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2014

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
Last Updated

March 24, 2014

Status Verified

March 1, 2014

Enrollment Period

3 years

First QC Date

March 19, 2014

Last Update Submit

March 20, 2014

Conditions

Keywords

Routine Outcome MonitoringPsychotherapyAllianceFeedback Informed TreatmentMental Health Outpatients

Outcome Measures

Primary Outcomes (1)

  • Overall clinical well-being as measured by the CORE-OM rating scale

    The CORE-OM is a short questionnaire that addresses broad psychiatric symptoms including depression, anxiety, well-being, vocational and domestic functioning, social problems, etc.

    up to 3 years follow-up

Secondary Outcomes (1)

  • Hospitalization rates

    up to three years of follow-up

Study Arms (2)

Frequent Monitoring and Feedback

ACTIVE COMPARATOR

In the intervention arm, patients routinely fill short monitoring questionnaires, the results of which are fed back to their therapists and staff. The frequency of monitoring is between once a week to once every three months, depending on the type of therapy

Behavioral: Frequent monitoring and feedback

Infrequent monitoring without feedback

SHAM COMPARATOR

In the control arm, patients will infrequently fill short monitoring questionnaires, the results of which are not fed back to their therapists and staff. The frequency of monitoring is between about once a year

Behavioral: Frequent monitoring and feedback

Interventions

In the intervention arm, patients routinely fill short monitoring questionnaires, the results of which are fed back to their therapists and staff. The frequency of monitoring is between once a week to once every three months, depending on the type of therapy

Frequent Monitoring and FeedbackInfrequent monitoring without feedback

Eligibility Criteria

Age6 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients undergoing intake to the clinic and beginning therapy

You may not qualify if:

  • Mental retardation or dementia
  • Hebrew Illiteracy
  • Adults who are not under their own legal custody
  • Not being able to fulfill the questionnaires with minor help

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shalvata Mental Health Center Outpatient clinics

Hod HaSharon, Israel

Location

MeSH Terms

Conditions

Mood DisordersAnxiety DisordersPsychotic DisordersPersonality Disorders

Condition Hierarchy (Ancestors)

Mental DisordersSchizophrenia Spectrum and Other Psychotic Disorders

Central Study Contacts

Lior Biran, Clinical Psychologist

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ori Ganor, MD

Study Record Dates

First Submitted

March 19, 2014

First Posted

March 24, 2014

Study Start

July 1, 2014

Primary Completion

July 1, 2017

Last Updated

March 24, 2014

Record last verified: 2014-03

Locations