ABATE
Cluster-Randomized Controlled Trial of Hospitals to Reduce Healthcare-Associated Infections and Readmissions Through Routine Bathing With Antiseptic Soap and Targeted Use of Nasal Antibiotic Ointment (ABATE Infection Trial)
Sponsor study identifier
Secondary identifiers
NIH
NIH
interventional
53
1 country
52
Study Start
April 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
February 2019
Actual (reported)Study Completion
February 2019
Actual (reported)The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units. The two strategies to be evaluated are:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 12, 2014
Actual (reported)February 14, 2014
Actual (reported)April 2014
Date type not reportedThis date has not been verified as actual or estimated.
February 2019
Actual (reported)February 2019
Actual (reported)July 12, 2019
Actual (reported)MRSA and VRE Clinical Cultures
Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) clinical cultures attributable to participating units. Defined as occurring \>2 days into a participating unit stay through 2 days following unit discharge
21 months
Gram-negative Multi-drug Resistant Organism Clinical Cultures
21 months
All-cause Bloodstream Infections
21 months
Routine policy for showering or bathing non-critical care patients
Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients. Topical intranasal mupirocin ointment (bilateral nares, twice daily) x5 days if non-critical care patients are MRSA+ by history, culture, or screen.
Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients. Topical intranasal mupirocin ointment (bilateral nares, twice daily) x5 days if non-critical care patients are MRSA+ by history, culture, or screen.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
West Hills Hospital & Medical Center
West Hills, California, 91307, United States
North Suburban Medical Center
Thornton, Colorado, 80229, United States
Blake Medical Center
Bradenton, Florida, 34209, United States
Osceola Regional Medical Center
Kissimmee, Florida, 34741, United States
Palms West Hospital
Loxahatchee Groves, Florida, 33470, United States
Orange Park Medical Center
Orange Park, Florida, 32073, United States
West Florida Hospital
Pensacola, Florida, 32514, United States
Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Heim L, Gombosev A, Avery TR, Haffenreffer K, Shimelman L, Hayden MK, Weinstein RA, Spencer-Smith C, Kaganov RE, Murphy MV, Forehand T, Lankiewicz J, Coady MH, Portillo L, Sarup-Patel J, Jernigan JA, Perlin JB, Platt R; ABATE Infection trial team. Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial. Lancet. 2019 Mar 23;393(10177):1205-1215. doi: 10.1016/S0140-6736(18)32593-5. Epub 2019 Mar 5.
Johnson KE, Neta G, Dember LM, Coronado GD, Suls J, Chambers DA, Rundell S, Smith DH, Liu B, Taplin S, Stoney CM, Farrell MM, Glasgow RE. Use of PRECIS ratings in the National Institutes of Health (NIH) Health Care Systems Research Collaboratory. Trials. 2016 Jan 16;17:32. doi: 10.1186/s13063-016-1158-y.
Susan Huang, MD MPH
University of California, Irvine
Ken Kleinman, ScD
University of Massachusetts, Amherst
Edward Septimus, MD
Hospital Corporation of America
Jason Hickok, MBA, RN
Hospital Corporation of America
53 participants (actual enrollment reported by the registry).
First Submitted
February 12, 2014
First Posted
February 14, 2014
Study Start
April 2014
Date type not reportedThis date has not been verified as actual or estimated.
Trial of MRSA Polymerase Chain Reaction for Pneumonia
Urinary Tract Infections
21 months
Blood Culture Contamination
21 months
Clostridium Difficile Infection
21 months
Contact the study team to confirm eligibility.
Northside Hospital
St. Petersburg, Florida, 33709, United States
St. Petersburg General Hospital
St. Petersburg, Florida, 33710, United States
South Bay Hospital
Sun City Center, Florida, 33573, United States
West Palm Hospital
West Palm Beach, Florida, 33407, United States
Cartersville Medical Center
Cartersville, Georgia, 30120, United States
Coliseum Northside Hospital
Macon, Georgia, 31210, United States
Eastside Medical Center
Snellville, Georgia, 30078, United States
Overland Park Regional Medical Center
Overland Park, Kansas, 66215, United States
Regional Medical Center of Acadiana
Lafayette, Louisiana, 70506, United States
Garden Park Medical Center
Gulfport, Mississippi, 39503, United States
Research Medical Center
Kansas City, Missouri, 64132, United States
Lee's Summit Medical Center
Lee's Summit, Missouri, 64063, United States
Sunrise Hospital and Medical Center
Las Vegas, Nevada, 89109, United States
MountainView Hospital-Las Vegas
Las Vegas, Nevada, 89128, United States
Parkland Medical Center
Derry, New Hampshire, 03038, United States
Portsmouth Regional Hospital
Portsmouth, New Hampshire, 03801, United States
Colleton Medical Center
Walterboro, South Carolina, 29488, United States
Parkridge Medical Center
Chattanooga, Tennessee, 37404, United States
Parkridge East Hospital
Chattanooga, Tennessee, 37412, United States
TriStar Horizon Medical Center
Dickson, Tennessee, 37055, United States
Hendersonville Medical Center
Hendersonville, Tennessee, 37075, United States
Summit Medical Center
Hermitage, Tennessee, 37076, United States
St. David's Medical Center
Austin, Texas, 78705, United States
Valley Regional Medical Center
Brownsville, Texas, 78526, United States
Conroe Regional Medical Center
Conroe, Texas, 77304, United States
Corpus Christi Medical Center
Corpus Christi, Texas, 78411, United States
Las Palmas Medical Center
El Paso, Texas, 79902, United States
Plaza Medical Center of Fort Worth
Fort Worth, Texas, 76104, United States
Las Colinas Medical Center
Irving, Texas, 75039, United States
Kingwood Medical Center
Kingwood, Texas, 77339, United States
Northeast Methodist Hospital
Live Oak, Texas, 78233, United States
Rio Grande Regional Hospital
McAllen, Texas, 78503, United States
North Hills Hospital
North Richland Hills, Texas, 76180, United States
Medical Center of Plano
Plano, Texas, 75075, United States
Methodist Texsan Hospital
San Antonio, Texas, 78201, United States
Methodist Hospital
San Antonio, Texas, 78229, United States
Methodist Specialty and Transplant Hospital
San Antonio, Texas, 78229, United States
Methodist Stone Oak Hospital
San Antonio, Texas, 78258, United States
Clear Lake Regional Medical Center
Webster, Texas, 77598, United States
Timpanogos Regional Hospital
Orem, Utah, 84057, United States
John Randolph Medical Center
Hopewell, Virginia, 23860, United States
LewisGale Hospital-Alleghany
Low Moor, Virginia, 24457, United States
Reston Hospital Center
Reston, Virginia, 20190, United States
Chippenham Johnston Willis Medical Center
Richmond, Virginia, 23225, United States
Henrico Doctors' Hospital
Richmond, Virginia, 23229, United States
Julia Moody, MS
Hospital Corporation of America
Mary Hayden, MD
Rush University
Robert Weinstein, MD
John Stroger Hospital
John Jernigan, MD MS
Centers for Disease Control and Prevention
Jonathan Perlin, MD PhD
Hospital Corporation of America
Daniel Gillen, PhD
University of California, Irvine
Grace Lee, MD MPH
Harvard Pilgrim Health Care Institute
Primary Completion
February 2019
Actual (reported)Study Completion
February 2019
Actual (reported)Last Updated
July 12, 2019
Results First Posted
July 12, 2019
Record last verified: 2019-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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