NCT02050477

Brief Summary

Evaluation of the laparoscopic approach of the Magenstrasse and Mill procedure in a prospective study of 100 patients

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for phase_4 obesity

Timeline
Completed

Started Jun 2012

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2012

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 25, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 30, 2014

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

January 30, 2014

Status Verified

January 1, 2014

Enrollment Period

2.1 years

First QC Date

January 25, 2014

Last Update Submit

January 28, 2014

Conditions

Keywords

ObesityBariatricSurgerySleeveGastroplastyLaparoscopy

Outcome Measures

Primary Outcomes (2)

  • Morbidity/Mortality

    1 month

  • Effect of the procedure on weight loss

    Evaluation at 1,3,6 and 12 months through clinical evaluation.

    1 year

Secondary Outcomes (2)

  • Reflux disease

    1 year

  • Effect of procedure on obesity associated co-morbidities

    1 year

Study Arms (1)

Laparoscopic Vertical Gastroplasty

EXPERIMENTAL
Procedure: Laparoscopic Vertical Gastroplasty

Interventions

The Magenstrasse and Mill procedure is a conservative vertical gastroplasty described in 1987 through a laparotomy. A tubular gastric pouch is created by a vertical stapling extending from the antrum to the angle of Hiss. In this study, we evaluate the laparoscopic technique of the procedure.

Laparoscopic Vertical Gastroplasty

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Assessment by a multidisciplinary team specialized in bariatric and metabolic surgery including surgeon, endocrinologist, psychologist and/or psychiatrist, dietician
  • BMI\>40
  • BMI\>35 with diabetes or sleep apnea syndrome or hypertension treated with 3 drugs for at least one year
  • Male or female patients between 18 and 75 years of age; fertile female patients must use a reliable contraception method;
  • No previous bariatric procedure
  • Informed consent given by patient

You may not qualify if:

  • Medical contra-indication for a general anesthesia, or abdominal surgery (allergies to anesthetic drugs, cardio-vascular, pulmonary, or renal conditions leading to an unacceptable risk for the procedure
  • Psychological-Psychiatric (boulimia, severe depression, psychotic condition)
  • Non stabilized endocrine disorder, with potential interference on weight and/or diabetic condition
  • Unability to understand goal of the study, plan of treatment and follow-up
  • Large hiatal hernia and/or severe esophageal reflux disease
  • Grazer, Sweet eater behavior

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept of Abdominal Surgery and Transplantation, CHU Liège

Liège, Liège, 4000, Belgium

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Arnaud De Roover, MD

    Dept of Abdominal Surgery and Transplantation CHU Liège Belgium

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professeur de Clinique, Chef de Clinique

Study Record Dates

First Submitted

January 25, 2014

First Posted

January 30, 2014

Study Start

June 1, 2012

Primary Completion

July 1, 2014

Study Completion

July 1, 2014

Last Updated

January 30, 2014

Record last verified: 2014-01

Locations