NCT01700738

Brief Summary

MAIN OBJECTIVE To compare the effects of the placement of an adjustable gastric band with "conventional" treatment of obesity. SECONDARY OBJECTIVES

  • Compare the effects of the placement of a gastric band with "conventional" treatment of obesity on quality of life, body composition and parameters of the metabolic syndrome.
  • Identify predictors of "good answer to the ring" to determine the best future indications.
  • Study of the gastric tolerance. INCLUSION CRITERIA
  • Adolescents 12 to 16 years and with BMI and weight gain according to sex and age is greater than IMCZ-score \> 4 DP\> 8 kg
  • Obesity "common" non-syndromic.
  • Medical decision of surgical placement of laparoscopic gastric banding.
  • Adolescent and family who understand and accept the need for medical and surgical follow long term.
  • Adolescent and family who fully understood the oral and written information explaining the study and the need for prolonged follow-up.
  • Obtention of oral and written consent of the adolescent and the parents.
  • Parents and adolescents affiliated with the social security system.
  • Intellectual Deficit.
  • psychiatrics contraindication of surgical placement of laparoscopic gastric banding.
  • Obesity with severe binge eating.
  • Pregnancy or wishes of pregnancy in the following year.
  • Non accession adolescent and / or family in the process of medical care before inclusion.
  • Predictable post surgical monitoring difficulties.
  • Suspicion of physical abuse, verbal or negligence / deficiency in care of the family.
  • Participation in a clinical study evaluating a treatment during the 2 years of the study.
  • Anesthetic contre indication for placement of a gastric laparoscopic.
  • IMC\> 50 kg/m2 the day of inclusion.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for phase_4 obesity

Timeline
Completed

Started Nov 2012

Typical duration for phase_4 obesity

Geographic Reach
1 country

6 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 2, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 4, 2012

Completed
28 days until next milestone

Study Start

First participant enrolled

November 1, 2012

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

October 4, 2012

Status Verified

October 1, 2012

Enrollment Period

3 years

First QC Date

October 2, 2012

Last Update Submit

October 2, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • BMIZ-score evolution in 2 years.

    2 years

Secondary Outcomes (9)

  • Evolution of quality of life scales

    1, 2, 5 and 10 years

  • Evaluation of des alimentary attitudinal troubles and psychiatrical troubles

    1 year

  • Evolution of BMIZ-score

    1, 5 and 10 years

  • Evolution of round-waist

    1, 2, 5 and 10 years

  • Evolution of bodily composition.

    1, 2, 5 and 10 years

  • +4 more secondary outcomes

Study Arms (2)

gastric ring surgery

EXPERIMENTAL

in this group a gastric ring will be put by surgery.

Procedure: gastric ring surgery

nutritional help

ACTIVE COMPARATOR

the usual treatment of obesity in France with nutritional care will be dispensed for this arm

Other: nutritional help

Interventions

gastric ring surgery
nutritional help

Eligibility Criteria

Age12 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Adolescents 12 to 16 years and with BMI and weight gain according to sex and age is greater than IMCZ-score \> 4 DP\> 8 kg
  • Obesity "common" non-syndromic.
  • Medical decision of surgical placement of laparoscopic gastric banding.
  • Adolescent and family who understand and accept the need for medical and surgical follow long term.
  • Adolescent and family who fully understood the oral and written information explaining the study and the need for prolonged follow-up.
  • Obtention of oral and written consent of the adolescent and the parents.
  • Parents and adolescents affiliated with the social security system.

You may not qualify if:

  • Intellectual Deficit.
  • psychiatrics contraindication of surgical placement of laparoscopic gastric banding.
  • Obesity with severe binge eating.
  • Pregnancy or wishes of pregnancy in the following year.
  • Predictable post surgical monitoring difficulties.
  • Suspicion of physical abuse, verbal or negligence / deficiency in care of the family.
  • Participation in a clinical study evaluating a treatment during the 2 years of the study.
  • Anesthetic contre indication for placement of a gastric laparoscopic.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

University Hospital of Angers

Angers, France, 49000, France

Location

University Hospital of Caen

Caen, 14033, France

Location

University hospital Bicêtre

Le Kremlin-Bicêtre, 94275, France

Location

University Hospital of Lille

Lille, 59037, France

Location

University Hospital of Necker

Paris, 75743, France

Location

University Hospital of Toulouse

Toulouse, 31059, France

Location

Related Publications (1)

  • Pourcher G, De Filippo G, Ferretti S, Piquard C, Dagher I, Bougneres P. Short-term results of single-port sleeve gastrectomy in adolescents with severe obesity. Surg Obes Relat Dis. 2015 Jan-Feb;11(1):65-9. doi: 10.1016/j.soard.2014.05.029. Epub 2014 Jun 3.

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • REGIS COUTANT

    UNIVERSITY HOSPITAL OF ANGERS

    PRINCIPAL INVESTIGATOR

Central Study Contacts

REGIS COUTANT

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 2, 2012

First Posted

October 4, 2012

Study Start

November 1, 2012

Primary Completion

November 1, 2015

Study Completion

November 1, 2015

Last Updated

October 4, 2012

Record last verified: 2012-10

Locations