The Effect of a Multi-component Weight Management Program on Appetite, Food Preference and Body Weight
SWSS
2 other identifiers
interventional
96
1 country
1
Brief Summary
The aim of the current study is to demonstrate that a commercial weight management diet (i.e. low energy density) influences satiation, hunger and satiety and leads to lower energy intake during ad-libitum meals and over a full day. We further seek to demonstrate the sustainability of this effect following 12- week weight loss on the weight management program.
- We hypothesise that formulated (low energy) meals will lead to decreased hunger, greater fullness and reduced desire to eat compared to standard meals.
- We hypothesise that the commercial weight management program will lead to greater weight loss compared to control program.
- We hypothesise that formulated meals (high consumer acceptance) will improve hedonic control over eating (lower wanting for high fat food)
- We hypothesise that the commercial weight management program will improve hedonic control over eating (reduced experience food cravings)
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2014
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 10, 2013
CompletedFirst Posted
Study publicly available on registry
December 16, 2013
CompletedStudy Start
First participant enrolled
January 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedJune 1, 2017
May 1, 2017
1.9 years
December 10, 2013
May 31, 2017
Conditions
Outcome Measures
Primary Outcomes (4)
Test Meal Energy Intake
Measured reductions in ad-libitum energy intake following consumption of formulated test meal in comparison to control.
Week 0 and week 12
24h Energy Intake
Measured reduction in total within-day energy intake following consumption of formulated meals in comparison to control
Week 0 and week 12
Appetite sensations
Measured reduction in hunger and increase in satiety quotient following consumption of formulated test meal in comparison to equi-energetic control
Week 0 and week 14
Food preference
Measured changes in food preference and liking and wanting profiles for food (HF\<LF) following consumption of formulated test meal in comparison to equi-energetic control
Week 0 and week 14
Secondary Outcomes (1)
Body Weight
Weekly from week 0 to week 12
Other Outcomes (3)
Food diary
Week 0 and week 12
Accelerometer
Week 0 and week 12
Interview
Week 12
Study Arms (2)
Intervention Group
EXPERIMENTALParticipants enrolled in commercial weight management program
Control group
ACTIVE COMPARATORParticipants enrolled in standard care weight management provision
Interventions
Eligibility Criteria
You may qualify if:
- BMI of 28 - 45 kg/m2
- Reporting an interest in weight loss, not actively participating in a commercial weight loss program,
- Not increased physical activity levels in the past 2-4 weeks
- Able to eat most everyday foods and fruits and vegetables
- Written informed consent to be given
You may not qualify if:
- Significant health problems that could cause confounding effects between intervention and control.
- Taking any medication or supplements known to affect appetite or weight within the past month and/or during the study
- Pregnant, planning to become pregnant or breastfeeding
- History of anaphylaxis to food
- Known food allergies or food intolerance
- Smokers and those who have recently ceased smoking
- Participants receiving systemic or local treatment likely to interfere with evaluation of the study parameters
- Those who have previously taken part in a commercial weight loss program in the last 6 months? .
- Participants who work in appetite or feeding related areas
- Participants unable to consume foods used in the study
- Participants who have had bariatric surgery
- Participants with a history of eating disorder
- Presence of untreated hypothyroidism
- Inability to fully comply with intervention or study procedures
- Insufficient English language skills to complete study questionnaires
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Leeds
Leeds, West Yorkshire, LS2 9JT, United Kingdom
Related Publications (2)
Buckland NJ, Camidge D, Croden F, Myers A, Lavin JH, Stubbs RJ, Blundell JE, Finlayson G. Women with a low-satiety phenotype show impaired appetite control and greater resistance to weight loss. Br J Nutr. 2019 Oct 28;122(8):951-959. doi: 10.1017/S000711451900179X.
PMID: 31340872DERIVEDBuckland NJ, Camidge D, Croden F, Lavin JH, Stubbs RJ, Hetherington MM, Blundell JE, Finlayson G. A Low Energy-Dense Diet in the Context of a Weight-Management Program Affects Appetite Control in Overweight and Obese Women. J Nutr. 2018 May 1;148(5):798-806. doi: 10.1093/jn/nxy041.
PMID: 30053284DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Graham S Finlayson, PhD
University of Leeds
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 10, 2013
First Posted
December 16, 2013
Study Start
January 1, 2014
Primary Completion
December 1, 2015
Study Completion
May 1, 2016
Last Updated
June 1, 2017
Record last verified: 2017-05