NCT01985529

Brief Summary

The effectiveness of clinic-based pulmonary rehabilitation in advanced Chronic Obstructive Pulmonary Disease (COPD) is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program was feasible and effective for patients with moderate COPD.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
19

participants targeted

Target at below P25 for not_applicable chronic-obstructive-pulmonary-disease

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2008

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

November 1, 2013

Completed
14 days until next milestone

First Posted

Study publicly available on registry

November 15, 2013

Completed
Last Updated

November 15, 2013

Status Verified

November 1, 2013

Enrollment Period

3 years

First QC Date

November 1, 2013

Last Update Submit

November 8, 2013

Conditions

Chronic Obstructive Pulmonary Disease

Outcome Measures

Primary Outcomes (1)

  • Endurance

    Change in endurance of physical activity was measured in seconds.

    12 weeks

Secondary Outcomes (1)

  • Muscle Strength

    12 weeks

Study Arms (2)

Exercise

EXPERIMENTAL

Enrollment in pulmonary rehabilitation

Other: Exercise

Control

NO INTERVENTION

Interventions

ExerciseOTHER
Exercise

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • patients with moderate COPD and self-reported exercise impairment

You may not qualify if:

  • current smokers, pulmonary diseases other than COPD, use of supplemental oxygen, musculoskeletal disease that impaired exercise performance and unstable coronary artery disease or congestive heart failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCLA

Westwood, Los Angeles, California, 90095, United States

Location

Related Publications (1)

  • Amin S, Abrazado M, Quinn M, Storer TW, Tseng CH, Cooper CB. A controlled study of community-based exercise training in patients with moderate COPD. BMC Pulm Med. 2014 Aug 4;14:125. doi: 10.1186/1471-2466-14-125.

    PMID: 25088030DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Exercise

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Christopher Cooper, MD

    University of California, Los Angeles

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Author

Study Record Dates

First Submitted

November 1, 2013

First Posted

November 15, 2013

Study Start

December 1, 2008

Primary Completion

December 1, 2011

Last Updated

November 15, 2013

Record last verified: 2013-11

Locations

US(1)