NCT01905319

Brief Summary

Aims of the study:

  • to study the incidence rate of juvenile idiopathic arthritis (JIA) and it's clinical subtypes in Estonia for the years 1998-2000;
  • to examine the course and short-term clinical outcome of JIA. Method: a prospective population-based study carried on in 14 counties of Estonia

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
162

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 1998

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1998

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2000

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2002

Completed
10.6 years until next milestone

First Submitted

Initial submission to the registry

July 16, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 23, 2013

Completed
Last Updated

March 25, 2020

Status Verified

March 1, 2020

Enrollment Period

2.9 years

First QC Date

July 16, 2013

Last Update Submit

March 23, 2020

Conditions

Epidemiology

Keywords

juvenile idiopathic arthritisincidence rate

Outcome Measures

Primary Outcomes (1)

  • Mean annual incidence rate of juvenile idiopathic arthritis in Estonia during years 1998-2000.

    3 years

Study Arms (1)

Subsequent new juvenile arthritis cases

During years 1998-2000, all new subsequent cases of juvenile idiopathic arthritis diagnosed in Estonia were included in the study group.

Other: Blood collecting for storage of samples

Interventions

Blood collecting for storage of samplesOTHER
Subsequent new juvenile arthritis cases

Eligibility Criteria

Age1 Month - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

During years 1998-2000, 162 newly-diagnosed juvenile idiopathic arthritis cases from 14 counties of Estonia, were included to the study, among them 76 boys and 86 girls.

You may qualify if:

  • The International League of Associations for Rheumatology (ILAR) criteria for juvenile idiopathic arthritis
  • children aged 0-15 years who had arthritis of an unknown cause for at least six weeks with an onset of the disease during the study period

You may not qualify if:

  • Children with infectious arthritis, postinfectious arthritis, traumatic arthritis and systemic connective tissue diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Pullerits R, Schierbeck H, Uibo K, Liivamagi H, Tarraste S, Talvik T, Sundberg E, Pruunsild C. High mobility group box protein 1-A prognostic marker for structural joint damage in 10-year follow-up of patients with juvenile idiopathic arthritis. Semin Arthritis Rheum. 2017 Feb;46(4):444-450. doi: 10.1016/j.semarthrit.2016.08.017. Epub 2016 Aug 26.

    PMID: 27756498DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Sera and plasma.

MeSH Terms

Conditions

Arthritis, Juvenile

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

July 16, 2013

First Posted

July 23, 2013

Study Start

January 1, 1998

Primary Completion

December 1, 2000

Study Completion

December 1, 2002

Last Updated

March 25, 2020

Record last verified: 2020-03