Obesity and Mortality
2 other identifiers
observational
311,982
0 countries
N/A
Brief Summary
Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2008
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2008
CompletedFirst Submitted
Initial submission to the registry
June 20, 2013
CompletedFirst Posted
Study publicly available on registry
June 28, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedAugust 25, 2014
August 1, 2014
5.9 years
June 20, 2013
August 21, 2014
Conditions
Outcome Measures
Primary Outcomes (1)
Change in Years of Life Lost Associated with Standard BMI categories Over Calendar Time
Between 1960 and 2000 (up to 40 years)
Secondary Outcomes (1)
Change in Adjusted Hazard Ratio Over Calendar Time for Standard BMI Categories
Between 1960 and 2000 (up to 40 years)
Study Arms (19)
Multiple Risk Factor Intervention Trial - Usual Group
Multiple Risk Factor Intervention Trial - Referred Group
Framingham Heart study
Framingham Offspring cohort
Atherosclerosis Risk In Communities
Charleston Heart study
Cardiovascular Health study
Rancho Bernardo study
Nurses' Health I study
Panel Study Income Dynamics
MRFIT Referred Care
HDFP Referral Care
Alameda County Health and Ways of Living Study
Nurses' Health II study
Tecumseh County Health study
EPESE-East Boston
Established Populations for Epidemiologic Studies of the Elderly-East Boston
EPESE-Duke
Established Populations for Epidemiologic Studies of the Elderly-Duke
EPESE-Iowa
Established Populations for Epidemiologic Studies of the Elderly-Iowa
EPESE-New Haven
Established Populations for Epidemiologic Studies of the Elderly-New Haven
Eligibility Criteria
U.S. based prospective cohorts of adults
You may qualify if:
- U.S. based studies with at least 1500 subjects
- At least 5 years of mortality follow-up
- BMI measured or self-reported available at 2 or more separate calendar time
- Subjects varied in age at baseline
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
David B Allison, Ph.D.
University of Alabama at Birmingham
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
June 20, 2013
First Posted
June 28, 2013
Study Start
January 1, 2008
Primary Completion
December 1, 2013
Study Completion
December 1, 2013
Last Updated
August 25, 2014
Record last verified: 2014-08