NCT01886911

Brief Summary

This project is focused on the neural and behavioral correlates of two different videos games that will be used as training tools. The two video games, developed by the Games Learning Society research group at the University of Wisconsin-Madison (UW) and the Wisconsin Institute for Discovery, are tailored to train mindfulness, particularly the regulation of attention; and prosocial behavior, especially sensitivity to others, in adolescents. This study will evaluate the hypothesis that systematic playing of mindfulness and prosocial games will change brain function in specific attentional, social and emotional circuits in potentially beneficial ways, and will impact performance on cognitive tasks of attention, and on measures of social cue perception and the propensity to share and behave altruistically. The investigators will employ behavioral and functional MRI-based neuroimaging measures to evaluate the investigators hypothesis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
192

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2013

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

June 19, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 26, 2013

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2014

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

October 2, 2015

Status Verified

June 1, 2015

Enrollment Period

9 months

First QC Date

June 19, 2013

Last Update Submit

September 30, 2015

Conditions

Keywords

prosocial behaviorprosocialattention trainingattentionempathyemotion recognition

Outcome Measures

Primary Outcomes (2)

  • Change from baseline in behavioral measures

    Change in behavioral measures before and after attentional video game training. Timeframe is up to 7 days following the end of the 2 week game playing period.

    baseline and up to 3 weeks

  • Change from baseline in fMRI

    Change in fMRI neural markers of empathic accuracy before and after attentional video game training. Timeframe is up to 7 days following the 2 week game playing period.

    baseline and up to 3 weeks

Study Arms (4)

Control for Attention Intervention

ACTIVE COMPARATOR

Attentional Control Game is an active control group. We expect subjects in this group to play a control game for 2 weeks (plus or minus 7 days).

Other: Control for Attention Intervention

Prosocial Training Intervention Game

EXPERIMENTAL

The prosocial intervention group, which we expect will be play the experimental prosocial training game for 2 weeks (plus or minus 7 days).

Other: Prosocial Training Intervention Game

Attention Training Intervention Game

EXPERIMENTAL

The attention intervention group, which we expect will be play the experimental attention training game for 2 weeks (plus or minus 7 days).

Other: Attention Training Intervention Game

Control for Prosocial Intervention

ACTIVE COMPARATOR

This is an active control group. We expect subjects in this group to play a control game for 2 weeks (plus or minus 7 days).

Other: Control for Prosocial Intervention

Interventions

Also known as: Tenacity
Attention Training Intervention Game
Also known as: Crystals of Kaydor
Prosocial Training Intervention Game
Control for Attention Intervention
Control for Prosocial Intervention

Eligibility Criteria

Age12 Years - 15 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Fluent English speaker
  • Enrolled in 7th or 8th grade

You may not qualify if:

  • Currently on psychotropic medications

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin - Madison

Madison, Wisconsin, 53705, United States

Location

Related Publications (1)

  • Patsenko EG, Adluru N, Birn RM, Stodola DE, Kral TRA, Farajian R, Flook L, Burghy CA, Steinkuehler C, Davidson RJ. Mindfulness video game improves connectivity of the fronto-parietal attentional network in adolescents: A multi-modal imaging study. Sci Rep. 2019 Dec 10;9(1):18667. doi: 10.1038/s41598-019-53393-x.

MeSH Terms

Conditions

Adolescent BehaviorAltruism

Condition Hierarchy (Ancestors)

BehaviorSocial Behavior

Study Officials

  • Richard Davidson, PhD

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2013

First Posted

June 26, 2013

Study Start

June 1, 2013

Primary Completion

March 1, 2014

Study Completion

May 1, 2015

Last Updated

October 2, 2015

Record last verified: 2015-06

Locations