The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis Patients

NCT01877863 | Completed DMC

• 1 other identifier: E-25253
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to explore the impact of an intradialytic exercise program on functional capacity, aerobic capacity, strength, quality of life, depression, hospitalizations and intradialytic episodes of hypotension. The investigators would also like to look at the impact of exercise training over twelve weeks on hemoglobin levels as well as the clearance of potassium, phosphate and urea. Our hypothesis is that the above mentioned outcomes will positively improve over the twelve week intervention.

Conditions

End Stage Kidney Disease

Keywords

intradialytic exercise; hemodialysis

Outcome Measures

Primary Outcomes (1)

• Functional Capacity

  Functional capacity is measured by the DASI score which gives an estimated V02 peak in ml/min/kg. The difference between the mean score at baseline and 12 weeks will be determined.

  12 weeks

Secondary Outcomes (10)

• Aerobic capacity

  12 weeks

• Strength

  12 weeks

• Quality of life

  12 weeks

• Hospitalizations

  12 weeks

• Hypotension

  12 weeks

Study Arms (1)

intradialytic exercise

EXPERIMENTAL

baseline data prior to starting exercise program will be obtained and then compared to the data after 12 weeks of an intradialtyic biking program

Other: exercise

Interventions

exercise OTHER

12 weeks of intradialytic biking at Borg intensity 3 - 4 for 15 to 60 minutes on each dialysis run

Also known as: intradialytic exercise, intradialytic biking, biking on hemodialysis

intradialytic exercise

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Cardiac and hemodynamic stability
• Absence of severe musculoskeletal impairment
• Increased musculoskeletal weakness
• Vital signs within normal range for exercise
• Desire/motivated to exercise
• Clearance from nephrologist and Kinesiologist

You may not qualify if:

• Compromised cardiac profiles
• Hemodynamic instability
• Severe bone disease
• Medical conditions which contraindicate exercise

Sponsors & Collaborators

• University of Calgary: lead

Study Sites (1)

Northwest Dialysis Centre

Calgary, Alberta, T2L 2J8, Canada

Location

MeSH Terms

Conditions

Kidney Failure, Chronic

Interventions

Exercise

Condition Hierarchy (Ancestors)

Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Jennifer MacRae

  University of Calgary

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 27, 2013
• First Posted: June 14, 2013
• Study Start: May 1, 2013
• Primary Completion: December 1, 2013
• Last Updated: March 20, 2014

Record last verified: 2014-03

Locations

CA (1)