NCT02734394

Brief Summary

The purpose of this project is to help to manage the many cancer treatment side effects through cardiovascular and resistance exercise, and education with the goal of using program outcomes to contribute to current research.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P50-P75 for not_applicable cancer

Timeline
6mo left

Started Jun 2014

Longer than P75 for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress96%
Jun 2014Dec 2026

Study Start

First participant enrolled

June 1, 2014

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

February 9, 2016

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 12, 2016

Completed
9.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Expected
Last Updated

March 30, 2025

Status Verified

March 1, 2025

Enrollment Period

11.8 years

First QC Date

February 9, 2016

Last Update Submit

March 25, 2025

Conditions

Cancer

Keywords

exercisebody compositionmetabolismnutrition

Outcome Measures

Primary Outcomes (4)

  • Maximal Exercise Test

    Pre and post maximum workload using an electronic cycle ergometer in Watts

    24 sessions (12 weeks)

  • Upper and Lower Limb Strength

    pre and post strength in upper and lower limb muscles using a linear differential variable transducer (LVDT) measured in Newton.meters

    24 sessions (12 weeks)

  • Body Mass Index

    Pre and post body mass index (kg/m2)

    24 sessions (12 weeks)

  • Percent Body Fat

    Pre and Post percent body fat (units: %)

    24 sessions (12 weeks)

Secondary Outcomes (2)

  • Glucose

    24 sessions (12 weeks)

  • Lipids

    24 sessions (12 weeks)

Study Arms (1)

Cardiovascular and strength training exercise

EXPERIMENTAL

24 sessions (\~12 weeks) exercise

Behavioral: Exercise

Interventions

ExerciseBEHAVIORAL

Cardiovascular and resistance exercise training

Cardiovascular and strength training exercise

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • previously diagnosed with cancer and will currently be receiving some form of treatment (chemotherapy, radiation therapy or hormonal therapy)

You may not qualify if:

  • Physical / health factors that prohibit exercise or lack of medical clearance from physician

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Waterloo

Waterloo, Ontario, N2L 3G1, Canada

Location

MeSH Terms

Conditions

NeoplasmsMotor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Caryl Russell, MSc

    University of Waterloo

    PRINCIPAL INVESTIGATOR

  • Michael Sharratt, PhD

    University of Waterloo

    PRINCIPAL INVESTIGATOR

  • Marina Mourtzakis, PhD

    University of Waterloo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research and Operations Manager

Study Record Dates

First Submitted

February 9, 2016

First Posted

April 12, 2016

Study Start

June 1, 2014

Primary Completion

March 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

March 30, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations

CA(1)