Ischaemic Stroke and Sleep Apnea in Northern Part of Finland

NCT01861275 | Completed DMC

• 2 other identifiers: 36/201336/2013 UO
• Study Type: observational
• Target: 256
• Locations: 1 country
• Sites: 1

Brief Summary

Obstructive sleep apnoea is a risk factor for ischaemic stroke. study hypothesis: In prospective study the investigators want to know how many ischaemic stroke patients have sleep apnoea and does thrombolysis play a role in severity of osa in six months follow up.

Conditions

Sleep Apnoea; Cerebral Palsy

Keywords

osa; cerebral palsy; thrombolysis in cerebral palsy; sleep registration

Outcome Measures

Primary Outcomes (1)

• cerebral palsy events and severity of osa

  in prospective study outcome measure is severity of osa in 6months follow-up

  from six months to twenty four months

Study Arms (2)

Nasal CPAP

We want to study the nasal-cpap treatment and it's compliance in sleep apnea patients with ischaemic stroke.

Device: Nasal CPAP

no Nasal CPAP

No nasal-cpap in sleep apnea patients with ischaemic stroke.

Interventions

Nasal CPAP DEVICE

Nasal CPAP treatment for obstructive sleep apnoea

Nasal CPAP

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

residents of Oulu university hospital area. consecutive patient sampling

You may qualify if:

• over 18 years old patients that have cerebral palsy and are able to participate to the study.

You may not qualify if:

• no co-operation and need for intensive care unit

Sponsors & Collaborators

• University of Oulu: lead

Study Sites (1)

Oulu university hospital,department of neurology

Oulu, Northern Finland, 90029, Finland

Location

Related Publications (4)

• Huhtakangas JK, Saaresranta T, Vahanikkila H, Huhtakangas J. Nocturnal hypoxemia and central apneas increase mortality, but not recurrent ischemic events after ischemic stroke. Sleep Med. 2022 Sep;97:1-9. doi: 10.1016/j.sleep.2022.05.014. Epub 2022 May 23.

  PMID: 35679775 DERIVED

• Huhtakangas JK, Huhtakangas J, Bloigu R, Saaresranta T. Unattended sleep study in screening for sleep apnea in the acute phase of ischemic stroke. Sleep Med. 2020 Jan;65:121-126. doi: 10.1016/j.sleep.2019.08.002. Epub 2019 Aug 8.

  PMID: 31751906 DERIVED

• Huhtakangas JK, Saaresranta T, Bloigu R, Huhtakangas J. The Evolution of Sleep Apnea Six Months After Acute Ischemic Stroke and Thrombolysis. J Clin Sleep Med. 2018 Dec 15;14(12):2005-2011. doi: 10.5664/jcsm.7524. Erratum In: J Clin Sleep Med. 2020 May 15;16(5):837-838. doi: 10.5664/jcsm.8428.

  PMID: 30518443 DERIVED

• Huhtakangas JK, Huhtakangas J, Bloigu R, Saaresranta T. Prevalence of sleep apnea at the acute phase of ischemic stroke with or without thrombolysis. Sleep Med. 2017 Dec;40:40-46. doi: 10.1016/j.sleep.2017.08.018. Epub 2017 Oct 7.

  PMID: 29221777 DERIVED

MeSH Terms

Conditions

Sleep Apnea Syndromes; Cerebral Palsy; Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases

Study Officials

• Tarja Saaresranta, Md PhD

  University hospital of Turku

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 21, 2013
• First Posted: May 23, 2013
• Study Start: April 1, 2013
• Primary Completion: January 1, 2015
• Study Completion: January 1, 2015
• Last Updated: May 24, 2016

Record last verified: 2016-05

Data Sharing

• IPD Sharing: Will share

Locations

FI (1)