Abu Dhabi Sleep Apnea (ADSA) Study

NCT02403141 | Unknown

• 1 other identifier: IREC020
• Study Type: observational
• Target: 1,400
• Locations: 1 country
• Sites: 1

Brief Summary

Obstructive sleep apnoea (OSA) is a common medical problem which, despite increasing awareness, remains under-diagnosed. There is a close association between OSA and obesity; 60-70% of patients diagnosed with OSA are either obese or overweight \[1\]. OSA is also very common among patients with type 2 diabetes. Type 2 Diabetes Mellitus (T2DM) has reached epidemic status in the Gulf region. OSA worsens insulin resistance and leads to weight gain through sleep disturbance \[2\]. Several mechanisms have been proposed for the associations of OSA with diabetes and obesity \[3\]. At present there is little available information regarding the prevalence of OSA in the UAE, the relationship with T2DM and obesity, and the impact of OSA on health outcomes in the Emirati population. This research will explore these relationships and inform public health decisions regarding diagnostic pathways, service provision and treatment protocols.

Conditions

Sleep Apnoea

Outcome Measures

Primary Outcomes (1)

• Primary objective (Establishing the prevalence of OSA in the study population.)

  Establishing the prevalence of OSA in the study population.

  3 months

Study Arms (4)

Normal glucose tolerance

Patients with normal fasting glucose. Blood glucose less than 5.6mmol/L

Other: Questionnaire

Impaired fasting glycaemia

Patients with blood glucose between 5.6mmol/L - 7mmol/L

Other: Questionnaire

Type 2 diabetes

Patients with blood glucose higher than 7mmol/L and negative IA2 and GAD antibodies.

Other: Questionnaire

Type 1 diabetes

Patients on insulin and with positive IA2 and/or GAD antibodies.

Other: Questionnaire

Interventions

Questionnaire OTHER

Impaired fasting glycaemia; Normal glucose tolerance; Type 1 diabetes; Type 2 diabetes

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients over the age of 18 attending ICLDC will be offered the option of taking part in the study. Those agreeing to participate will be asked to fill in a questionnaire.

You may qualify if:

• Participants aged between 18-64 years old. Both Gender male and female.

You may not qualify if:

• Paediatrics below the age of 18. Any participant who is unable to take part

Sponsors & Collaborators

• Imperial College London Diabetes Centre: lead

Study Sites (1)

Imperial College London Diabetes Centre

Abu Dhabi, P.O Box 48338, United Arab Emirates

Location

MeSH Terms

Conditions

Sleep Apnea Syndromes

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Consultant Endocrinologist

Study Record Dates

• First Submitted: March 25, 2015
• First Posted: March 31, 2015
• Study Start: March 1, 2015
• Primary Completion: March 1, 2017
• Study Completion: March 1, 2017
• Last Updated: March 3, 2017

Record last verified: 2017-03

Locations

AE (1)