Glycaemic Index of Foods in Healthy Volunteers

NCT01833689 | Unknown DMC

• 1 other identifier: 13HH0549
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to assess the effect that dietary carbohydrates have on blood sugar by measuring the glycaemic index. The glycaemic index is a comparison between the effect of equal amounts of carbohydrate from a test food compared to a standard (in this case glucose) on blood sugar. Different foods that contain different carbohydrates have different effects on blood sugars. This is of interest as a number of studies have shown that the level of sugar in the blood after a meal relates directly to the risk of developing heart disease and diabetes. The aim of collecting this data is to be able to give advice to people about the carbohydrates they eat to reduce the risk of diabetes and heart disease.

Conditions

Healthy

Keywords

glucose response; glycaemic index

Outcome Measures

Primary Outcomes (1)

• glycaemic index

  1-2 months depending on product

Study Arms (2)

food consumption: control

PLACEBO COMPARATOR

The control product will be 50g glucose powder dissolved in 250ml of water

Dietary Supplement: food consumption

food consumption: product

ACTIVE COMPARATOR

The test food will provide 50g of available carbohydrate

Dietary Supplement: food consumption

Interventions

food consumption DIETARY_SUPPLEMENT

Reference food The reference food is 50 g glucose powder dissolved in 250ml water Test foods The test foods are prepared according to manufacturer's instructions, representing the food as normally consumed. The test foods are consumed once only on separate occasions as a portion providing 50g of available carbohydrate. Breakfast cereals should be consumed with 150 ml milk which is additional to the 50 g available carbohydrate in the cereal. In testing breakfast cereals, the reference food must also be consumed with an additional 150 ml milk.

food consumption: control; food consumption: product

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• BMI 18.5-27 kg/m2
• age 18-65 years
• healthy

You may not qualify if:

• diabetes
• chronic disease
• glucose impairment
• pregnancy

Sponsors & Collaborators

• Imperial College London: lead

Study Sites (1)

NIHR/Wellcome Trust Imperial CRF

London, W12 0HS, United Kingdom

RECRUITING

Study Officials

• Gary Frost, BSc SRD PhD

  Imperial College London

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gary Frost, BSc SRD PhD

CONTACT

020 8383 8037; g.frost@imperial.ac.uk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 12, 2013
• First Posted: April 17, 2013
• Study Start: June 1, 2013
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: August 14, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)