NCT01826734|Completed
Analysis of 86 Dacryoliths at the University Hospital Ostrava
Lacrimal Sac Dacryoliths (86 Samples): Chemical and Mineralogic Analyses
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Lacrimal Sac Dacryoliths (86 Samples): Chemical and Mineralogic Analyses
Sponsor study identifier
observational
86
1 country
1
Study Start
January 1994
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2012
Actual (reported)Study Completion
January 2013
Actual (reported)Background Because dacryoliths occur at low frequency, few studies have focused on their composition. The investigators aimed to present findings from morphological, chemical, and mineralogic analysis of 86 dacryoliths. Methods The team studied 86 dacryoliths obtained during 832 dacryocystorhinostomies (DCR) performed for postsaccal obstruction. The samples were analyzed with atomic infrared spectrometry (80 samples), amino acid analysis (17 samples), scanning electron microscopy, and an electron microprobe with an energy dispersive detector (7 samples).
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2013
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1994
Date type not reportedThis date has not been verified as actual or estimated.
December 2012
Actual (reported)January 2013
Actual (reported)March 22, 2013
Actual (reported)April 8, 2013
Actual (reported)The percentage of individual types of amino-acids in the dacryolits
The obtained dacryolist were assessed physically and chemically. The authors will assess the obtained material for the presence of common amino acids.
18 months
The percentage individual elements in the dacryolits
18 months
The study population consisted of patients following a dacryolit extraction procedure. The extraction procedure was not a part of this study.
The study population consisted of patients complaining of lacrimation, with subsequent detection and extraction of a dacryolit.
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, 70800, Czechia
Iliadelis ED, Karabatakis VE, Sofoniou MK. Dacryoliths in a series of dacryocystorhinostomies: histologic and chemical analysis. Eur J Ophthalmol. 2006 Sep-Oct;16(5):657-62.
Iliadelis E, Karabatakis V, Sofoniou M. Dacryoliths in chronic dacryocystitis and their composition (spectrophotometric analysis). Eur J Ophthalmol. 1999 Oct-Dec;9(4):266-8. doi: 10.1177/112067219900900402.
Lew H, Lee SY, Yun YS. Measurement of pH, electrolytes and electrophoretic studies of tear proteins in tears of patients with dacryoliths: a novel concept for dacryoliths. Ophthalmologica. 2004 Mar-Apr;218(2):130-5. doi: 10.1159/000076149.
Dacryolits during the DCR procedure.
Pavel Kominek, doc,MD,PhD,MBA
University Hospital Ostrava
86 participants (actual enrollment reported by the registry).
First Submitted
March 22, 2013
First Posted
April 8, 2013
Study Start
January 1994
Date type not reportedThis date has not been verified as actual or estimated.
Clinical Study of Lacrimal Drainage Obstruction Diseases Using Dacryoendoscopy
Contact the study team to confirm eligibility.
Kominek P, Doskarova S, Svagera Z, Lach K, Cervenka S, Zelenik K, Matousek P. Lacrimal sac dacryoliths (86 samples): chemical and mineralogic analyses. Graefes Arch Clin Exp Ophthalmol. 2014 Mar;252(3):523-9. doi: 10.1007/s00417-013-2501-6. Epub 2013 Oct 30.
Primary Completion
December 2012
Actual (reported)Study Completion
January 2013
Actual (reported)Last Updated
September 5, 2016
Record last verified: 2016-09
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