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Retrospective Data Analysis of Patients Undergoing Lacrimal Drainage System Interventions at The Department of Ophthalmology and Optometry During The Years 2013 - 2017
Sponsor study identifier
observational
625
1 country
1
Study Start
July 3, 2018
Actual (reported)Primary Completion
February 6, 2020
Actual (reported)Study Completion
June 11, 2020
Actual (reported)1.1 Background Obstructions of the lacrimal drainage system can be differentiated based on anatomical location or severity. But also, differentiating between congenital and acquired nasolacrimal duct obstruction (NLDO) is possible. The incidence of congenital NLDO (CNLOD) has been shown to be approximately 20%. Most of the cases undergo spontaneous remission, as the ductus nasolacrimalis may open spontaneously. About 2-12% display a symptomatic course. 2. S: 290; 3; 4, 5 Acquired NLDO may occur during childhood and adulthood. The incidence of symptomatic acquired NLDO is around 30 cases per 100.000 people in an US-based cohort study. S: 293; 30 Two major anatomical closure sites have been described, which are on the one hand located at the between the punctum and canaliculus, and on the other hand located after the lacrimal sac. 1. S. ; 2. S: 293 1.2 Aim of this study The aim of this study is to assess the success rates for different types of primary tear duct surgery, performed from 2013 - 2017 at the department of Ophthalmology and Optometry, Medical University of Vienna. Treatment success was defined as the absence of clinical signs of lacrimal drainage system obstruction (epiphora, increased tear leak, mucous discharge) and without the need for re-intervention. It is further investigated whether the type of operation performed or whether the silicone tube used influence success rates. 1.3 Methods A retrospective chart analysis of all patients - independent of the underlying pathology - undergoing surgery of the lacrimal drainage system between 1st of January 2013 and 31st December 2017. Success rates and patient profiles will be analyzed not only for all patients, but also for subgroups based on the underlying pathology and operation performed.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 11, 2020
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 3, 2018
Actual (reported)February 6, 2020
Actual (reported)June 11, 2020
Actual (reported)June 11, 2021
Actual (reported)June 18, 2021
Actual (reported)Success rate of NLDO interventions
1.1.2013 - 31.12.2017
Success rate of different surgical approaches
1.1.2013 - 31.12.2017
retrospective analysis of data
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Charts of all patients - independent of the underlying pathology - undergoing surgery of the lacrimal drainage system between 1st of January 2013 and 31st December 2017. We expect approximately 700 eyes of 500 patients.
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Medical University of Vienna
Vienna, 1090, Austria
625 participants (actual enrollment reported by the registry).
First Submitted
June 11, 2021
First Posted
June 18, 2021
Study Start
July 3, 2018
Actual (reported)Primary Completion
February 6, 2020
Actual (reported)Study Completion
June 11, 2020
Actual (reported)Last Updated
June 23, 2021
Record last verified: 2021-06
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Source: ClinicalTrials.gov.
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