Impact of an E-learning Tool on Patient Satisfaction, Knowledge and Medication Adherence in Solid Organ Transplantation: A Randomized Controlled Trial

NCT01826721 | Completed

• 1 other identifier: REB10-0987-AE
• Study Type: interventional
• Target: 246
• Locations: 1 country
• Sites: 1

Brief Summary

Solid organ transplant recipients (SOTR) must follow complex medication regimens and require a substantial amount of education for effective self-management. The current standard of care for post-transplant medication teaching is a Self Medication education program conducted in hospital by the pharmacist. The Transplant Medication Information Teaching Tool (TMITT) is a web-based e-learning tool for SOTR developed at the Toronto General Hospital. The ability to control the content, sequence, pace and timing of education in order to achieve personal learning objectives, as well as the opportunity for ongoing review and reinforcement of information, may be an attractive, convenient and effective teaching modality. SOTR will be randomly assigned to receive the standard of care or the standard of care plus the TMITT intervention. Primary objectives are to compare patient satisfaction and medication knowledge between the two groups at baseline and 3 months using modified versions of previously published questionnaires. Medication adherence as measured by a multidimensional approach including both subjective and objective components, will also be compared at 3 months. Our hypothesis is that an education strategy that includes both the standard pharmacist teaching followed by a tailored online e-learning intervention post-discharge will lead to improved patient satisfaction, knowledge and medication adherence.

Conditions

Solid Organ Transplantation

Keywords

Solid organ transplantation; Immunosuppression; Education; E-learning; Medication knowledge; Patient satisfaction; Medication adherence

Outcome Measures

Primary Outcomes (1)

• Change in Medication Knowledge Score from baseline to 3 months

  Medication Knowledge Score consists of 2 parts - recall of medication regimen and multiple choice knowledge questionnaire.

  Baseline and 3 months

Secondary Outcomes (2)

• Patient Satisfaction

  Baseline and 3 months

• Medication Adherence

  3 months

Study Arms (2)

Standard of Care

NO INTERVENTION

Patients in the Standard of Care arm receive the usual in-hospital post-transplant medication teaching class led by a transplant pharmacist.

TMITT

ACTIVE COMPARATOR

Patients in this arm receive the standard of care plus the TMITT educational intervention.

Other: Transplant Medication Information Teaching Tool

Interventions

Transplant Medication Information Teaching Tool OTHER

Online e-learning tool for post-transplant medication education.

TMITT

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• all patients undergoing solid organ transplantation at Toronto General Hospital during the study period

You may not qualify if:

• non-English speaking/reading
• no internet access at home
• planned discharge to a rehab facility without internet access
• not on a calcineurin inhibitor (CNI) or sirolimus
• attending the Self Medication class on the same day as hospital discharge
• cognitive impairment that precludes participation in Self Medication program (as per the assessment of the transplant pharmacist)
• incapable of providing informed consent

Sponsors & Collaborators

• Jennifer Harrison: lead

Study Sites (1)

Toronto General Hospital

Toronto, Ontario, M5G 2N2, Canada

Location

Related Publications (2)

• Mellon L, Doyle F, Hickey A, Ward KD, de Freitas DG, McCormick PA, O'Connell O, Conlon P. Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients. Cochrane Database Syst Rev. 2022 Sep 12;9(9):CD012854. doi: 10.1002/14651858.CD012854.pub2.

  PMID: 36094829 DERIVED

• Harrison JJ, Badr S, Hamandi B, Kim SJ. Randomized Controlled Trial of a Computer-Based Education Program in the Home for Solid Organ Transplant Recipients: Impact on Medication Knowledge, Satisfaction, and Adherence. Transplantation. 2017 Jun;101(6):1336-1343. doi: 10.1097/TP.0000000000001279.

  PMID: 27367473 DERIVED

Related Links

• Related Info

MeSH Terms

Conditions

Patient Satisfaction; Medication Adherence

Condition Hierarchy (Ancestors)

Treatment Adherence and Compliance; Health Behavior; Behavior; Patient Compliance; Patient Acceptance of Health Care

Study Officials

• Jennifer Harrison, BScPhm, MSc

  University Health Network, Toronto General Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Pharmacy Clinical Site Leader

Study Record Dates

• First Submitted: April 1, 2013
• First Posted: April 8, 2013
• Study Start: May 1, 2011
• Primary Completion: October 1, 2012
• Study Completion: March 1, 2013
• Last Updated: April 8, 2013

Record last verified: 2013-04

Locations

CA (1)