NCT01826409

Brief Summary

This study was conducted to investigate the effects of daily supplementation of fermented red ginseng (FRG) on glycemic status in subjects with impaired fasting glucose (IFG) or type 2 diabetes.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2008

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2009

Completed
3.6 years until next milestone

First Submitted

Initial submission to the registry

April 4, 2013

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 8, 2013

Completed
Last Updated

August 29, 2013

Status Verified

August 1, 2013

Enrollment Period

1.5 years

First QC Date

April 4, 2013

Last Update Submit

August 28, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Glucose profiles during meal tolerance test

    Fasting and postprandial glucose profiles during meal tolerance test were assessed before(baseline) and after the intervention

    4 weeks

Secondary Outcomes (1)

  • Change in lipid profiles

    4 weeks

Study Arms (2)

Fermented red ginseng

EXPERIMENTAL
Dietary Supplement: Fermented Red Ginseng

Placebo

PLACEBO COMPARATOR
Dietary Supplement: Placebo

Interventions

Fermented Red GinsengDIETARY_SUPPLEMENT

Fermented red ginseng 2.7g/day for 4 weeks

Fermented red ginseng
PlaceboDIETARY_SUPPLEMENT

Placebo 2.7g/day for 4 weeks

Placebo

Eligibility Criteria

Age20 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 20-75 years with fasting glucose 100\~140 mg/dL at least two of the following

You may not qualify if:

  • Lipid metabolic disorder
  • Acute or chronic inflammatory disease
  • Taking medication of corticosteroid within 4 weeks of the study
  • Cardiovascular disease (arrhythmia, heart failure, myocardial infarction or patient with pacemaker)
  • Allergic or hypersensitive to any of the ingredients in the test products
  • Participation in other clinical trials within 2 months
  • Abnormal hepatic liver function or renal disease (acute/chronic renal failure or nephrotic syndrome)
  • Taking medication of lipid phosphates within 3 months of the study etc,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clincial Trial Center for Functional Foods

Jeonju, Jeollabok-do, 560-822, South Korea

Location

Related Publications (1)

  • Oh MR, Park SH, Kim SY, Back HI, Kim MG, Jeon JY, Ha KC, Na WT, Cha YS, Park BH, Park TS, Chae SW. Postprandial glucose-lowering effects of fermented red ginseng in subjects with impaired fasting glucose or type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial. BMC Complement Altern Med. 2014 Jul 11;14:237. doi: 10.1186/1472-6882-14-237.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Tae Sun Park, MD., PhD

    Chonbuk National University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Clinical Trial Center for Functional Foods

Study Record Dates

First Submitted

April 4, 2013

First Posted

April 8, 2013

Study Start

March 1, 2008

Primary Completion

September 1, 2009

Last Updated

August 29, 2013

Record last verified: 2013-08

Locations