Cluster Analysis of the Risk of Metabolic Syndrome in Women for Reproductive Age

NCT01826357 | Unknown DMC

• 1 other identifier: Hsu2013-TMU-JIRB 201302002
• Study Type: observational
• Target: 700
• Locations: 1 country
• Sites: 1

Brief Summary

The metabolic syndrome (MetS) is a cluster of clinical indices that signals increased risk for cardiovascular disease and Type 2 diabetes. Women with polycystic ovary syndrome (PCOS) were associated with MetS and insulin resistance. Cluster analysis was a useful tool for identifying groups of women sharing similar metabolic risk factor patterns. Oligomenorrhea, hyperandrogenism and polycystic ovary morphology were the three major components of PCOS. Obesity is a main risk factor in metabolic syndrome. the investigators are interesting to evaluate the relationship between risk of metabolic syndrome and their clinical and/or biochemical characteristics in women with reproductive age. Design: Retrospective study; medical records reviewed. Participants and setting: The investigators retrospectively reviewed the medical records of female patients who visited our Reproductive Endocrinology Clinic from Jan. 1, 2009 to Jun. 31, 2012.

Conditions

Metabolic Cardiovascular Syndrome

Keywords

metabolic syndrome; cluster analysis; PCOS

Outcome Measures

Primary Outcomes (1)

• metabolic syndrome

  We conduct this retrospective study by using cluster analysis, to investigate the relationship between metabolic complications and biochemical/clinical characteristics of endocrinologic dysfunction in women with reproductive age.

  Retrospectively reviewed the patients who visited Reproductive Endocrinology Clinic from Jan. 1, 2009 to Jun. 31, 2012.

Eligibility Criteria

• Age: 13 Years - 48 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Women had been fulfilled with whole anthropometric measurements, clinic and biochemical survey about cardiovascular study.

You may qualify if:

• Women had been fulfilled with whole anthropometric measurements, clinic and biochemical survey about cardiovascular study.

You may not qualify if:

• women who had been diagnosed with malignant tumor, Asherman's syndrome, Mullerian agenesis, and chromosomal anomalies;
• women who had had menarche less than 1 years before evaluation or who were older than 49;
• women who received hormones or drugs for major medical diseases within three months of blood sampling.

Sponsors & Collaborators

• Taipei Medical University WanFang Hospital: lead

Study Sites (1)

WanFang Medical Center at Taipei Medical University

Taipei, Taiwan, 116, Taiwan

RECRUITING

Related Publications (1)

• Tzeng CR, Chang YC, Chang YC, Wang CW, Chen CH, Hsu MI. Cluster analysis of cardiovascular and metabolic risk factors in women of reproductive age. Fertil Steril. 2014 May;101(5):1404-10. doi: 10.1016/j.fertnstert.2014.01.023. Epub 2014 Feb 15.

  PMID: 24534286 DERIVED

MeSH Terms

Conditions

Metabolic Syndrome

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Ming I Hsu, MD

  WanFang Medical Center at Taipei Medical University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Taipei Medical University WanFang Hospital

Study Record Dates

• First Submitted: April 3, 2013
• First Posted: April 8, 2013
• Study Start: March 1, 2013
• Primary Completion: February 1, 2014
• Study Completion: February 1, 2014
• Last Updated: November 6, 2013

Record last verified: 2013-11

Locations

TW (1)