MaSS - Maastricht Sarcopenia Study

NCT01820988 | Completed

• 1 other identifier: METC 13-3-006
• Study Type: observational
• Target: 247
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this cross-sectional study is to obtain insight in the characteristics (nutritional status and level of physical activity) of sarcopenic compared to non-sarcopenic community-dwelling older people. There is one measurement moment and measurements will take place at the participant's home.

Conditions

Sarcopenia

Outcome Measures

Primary Outcomes (1)

• Mean difference in nutritional status and level of physical activity of sarcopenic participants vs. non-sarcopenic participants, as a measure of a Food Frequency Questionnaire and Mini-Nutritional Assessment Tool and Minnesota questionnaire

  1 home visit

Secondary Outcomes (3)

• Prevalence of sarcopenia in community-dwelling older people

  1 home visit

• Number of sarcopenic participants with frailty as a measure of the FRAIL scale and Fried criteria

  1 home visit

• Health care costs by sarcopenic vs. non-sarcopenic participants, measured by health care use

  1 home visit

Study Arms (1)

Sarcopenic vs. non-sarcopenic

Participants are classified as sarcopenic/non-sarcopenic according to the criteria of the European Working Group of Sarcopenia in Older People (EWGSOP).

Eligibility Criteria

• Age: 65 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Community-dwelling older people

You may qualify if:

• ≥ 65 years old
• Have given informed consent
• Understand Dutch language
• Able to perform a walk test

You may not qualify if:

• Older people living in a nursing home
• Older people with active rheumatoid arthritis, post stroke status with evident lingering symptoms (paralysis, loss of motor functions), diseases of the nervous system like Parkinson and MS, active angina pectoris, dementia
• Older people in a wheelchair, with ICD or pacemaker

Sponsors & Collaborators

• Maastricht University Medical Center: lead
• Nutricia Research Fundation: collaborator

Study Sites (1)

Maastricht University

Maastricht, Netherlands

Location

Related Publications (2)

• Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, Schoberer D, Cruz Jentoft AJ, van Loon LJ, Schols JM. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013 Mar;14(3):170-8. doi: 10.1016/j.jamda.2012.10.009. Epub 2012 Dec 29.

  PMID: 23276432 RESULT

• Mijnarends DM, Schols JM, Meijers JM, Tan FE, Verlaan S, Luiking YC, Morley JE, Halfens RJ. Instruments to assess sarcopenia and physical frailty in older people living in a community (care) setting: similarities and discrepancies. J Am Med Dir Assoc. 2015 Apr;16(4):301-8. doi: 10.1016/j.jamda.2014.11.011. Epub 2014 Dec 17.

  PMID: 25530211 RESULT

Biospecimen

Retention: SAMPLES WITH DNA

Blood sample.

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• J.M.G.A. Schols, Prof. Dr.

  Maastricht University

  STUDY DIRECTOR

• R.J.G. Halfens, PhD

  Maastricht University

  PRINCIPAL INVESTIGATOR

• J.M.M. Meijers, PhD

  Maastricht University

  PRINCIPAL INVESTIGATOR

• D.M. Mijnarends, MSc

  Maastricht University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 12, 2013
• First Posted: March 29, 2013
• Study Start: May 1, 2013
• Primary Completion: March 1, 2014
• Study Completion: December 1, 2015
• Last Updated: January 20, 2016

Record last verified: 2015-04

Locations

NL (1)